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中国应用生理学杂志 ›› 2018, Vol. 34 ›› Issue (2): 145-149.doi: 10.12047/j.cjap.5577.2018.036

• 研究论文 • 上一篇    下一篇

16周有氧运动对中老年baPWV及ABI的影响

李宁川1, 尹夏莲1, 韦秀霞1, 陆伟2, 沈诗文1, 肖浪1, 胡玉龙1   

  1. 1. 扬州大学体育学院, 江苏 扬州 225127;
    2. 苏州市高新区实验初级中学, 江苏 苏州 215011
  • 收稿日期:2017-03-03 修回日期:2017-11-01 出版日期:2018-03-28 发布日期:2018-05-22
  • 通讯作者: 李宁川 E-mail:linc@yzu.edu.cn
  • 基金资助:
    教育部人文社会科学研究规划基金(16YJA890009);扬州市重点研发计划-社会发展(YZ2015082)

Effects of 16 week aerobic exercise on baPWV and ABI of middle-aged and elderly patients

LI Ning-chuan1, YIN Xia-lian1, WEI Xiu-xia1, LU Wei2, SHEN Shi-wen1, XIAO Lang1, HU Yu-long1   

  1. 1. Physical Education College, Yangzhou University, Yangzhou 225127;
    2. Experimental Junior Middle School of Suzhou Hi-teach New District, Suzhou 215011, China
  • Received:2017-03-03 Revised:2017-11-01 Online:2018-03-28 Published:2018-05-22
  • Supported by:
    教育部人文社会科学研究规划基金(16YJA890009);扬州市重点研发计划-社会发展(YZ2015082)

摘要: 目的:探讨16周有氧运动锻炼对中老年动脉硬化的干预作用及相关机制。方法:以27名中老年人为研究对象,平均年龄(62.70 ±3.26)岁,采用每次60 min、每周6次,共16周的广场舞/太极拳进行锻炼,分别测试锻炼前和锻炼8周末、16周末受试者收缩压(SBP)、舒张压(DBP)、左肱踝动脉脉搏波传导速度(L-baPWV)、右肱踝动脉脉搏波传导速度(R-baPWV)、左踝臂血压指数(L-ABI)和右踝臂血压指数(R-ABI)的变化,并检测血清甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-c)、低密度脂蛋白胆固醇(LDL-c)、超氧化物歧化酶(SOD)、丙二醛(MDA)和谷胱甘肽过氧化物酶(GSH-Px)等相关指标的变化。结果:①与运动前相比,有氧运动锻炼8周末R-baPWV、R-ABI下降,16周末则L-baPWV、R-baPWV、R-ABI、L-ABI均呈显著性下降(P<0.01);②与运动前比,8周末SBP和DBP显著下降(P<0.05),16周末SBP、DBP和脉压差则显著降低(P<0.01,P<0.05);③与运动前相比,在8周末、16周末受试者TC、LDL-c均显著降低(P<0.01),HDL-c、TG在8周末和16周末的变化则无统计学意义;④与试验前相比,8周末血清SOD、GSH-Px、MDA无明显变化,16周末血清SOD、GSH-Px活性呈显著性升高、而血清MDA含量则呈显著性下降(P<0.01)。结论:通过16周有氧运动,可明显降低中老年人baPWV和ABI水平,调节血压、血脂及过氧化脂质水平,进而可能对动脉硬化程度起到一定的改善作用。

关键词: 有氧运动, 血压, 血脂, baPWV, ABI

Abstract: Objective:To investigate the interventional effects of 16-week aerobic exercises on the elderly's arteriosclerosis and its mechanism. Methods:Twenty-seven elderly people with the average age of 62. 70 ±3. 26 joined a 16-week square dance/taijiquan exercise program that conducted 60 minutes each time, six times per week. Arterial stiffness and its related indexes such as systolic pressure(SBP), diastolic pressure(DBP), left brachial-ankle pulse wave velocity (L-baPWV), right brachial-ankle pulse wave velocity(R-baPWV), left ankle brachial index (L-ABI), right ankle brachial index(R-ABI), serum triglyceride(TG), total cholesterol(TC), high density lipoprotein cholesterol(HDL-c), low density lipoprotein cholesterol(LDL-c), superoxide dismutase(SOD), malondialdehyde(MDA) and glutathione peroxidase (GSH-Px) were detected at 3 time points including before exercise program, by the end of exercise for 8 weeks and 16 weeks. Results:① Compared with pre-exercise, the R-baPWV and R-ABI of the elderly people were decreased at the end of the 8th week, and the L-baPWV, RbaPWV, R-ABI and L-ABI were decreased significantly at the end of the 16th week. ②Compared with pre-exercise, SBP and DBP were declined markedly (P<0.01, P<0.05) at the end of the 8th week, SBP, DBP and pulse pressure were decreased significantly (P<0.01, P<0.05) at the end of the 16th week. ③Compared with pre-exercise, TC and LDL-c were declined markedly (P<0.01) at the end of the 8th and the 16th week, and there was no difference of the level of TG and LDL-c between pre-exercise and post-exercise. ④There was no evident difference of serum level of SOD, GSH-Px, MDA between pre-exercise and post-exercise at the end of the 8th week. Compared with pre-exercise, the level of serum SOD, GSH-Px was increased evidently while the content of serum MDA was decreased significantly (P<0.01). Conclusion:Sixteen-week aerobic exercises could reduce baPWV and ABI levels, regulate blood pressure, blood lipids and lipid peroxides levels of the elderly evidently, thus improve the controlling quality of atherosclerosis.

Key words: aerobic exercise, blood pressure, blood lipids, brachial-ankle pulse wave velocity, ankle brachial index

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