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中国应用生理学杂志 ›› 2016, Vol. 32 ›› Issue (3): 284-288.doi: 10.13459/j.cnki.cjap.2016.03.026

• 研究简报 • 上一篇    

在生理学研究中如何正确估计样本含量

刘一松, 郭春雪, 胡完, 吕辰龙, 胡良平   

  1. 军事医学科学院生物医学统计学咨询中心, 北京 100850
  • 收稿日期:2015-06-15 修回日期:2015-10-12 出版日期:2016-05-28 发布日期:2018-06-12
  • 通讯作者: 胡良平,Tel:010-66932127;E-mail:lphu812@sina.com E-mail:lphu812@sina.com
  • 基金资助:
    胡良平,Tel:010-66932127;E-mail:lphu812@sina.com

How to scientifically estimate sample size in physiological research

LIU Yi-song, GUO Chun-xue, HU Wan, LV Chen-long, HU Liang-ping   

  1. Consulting Center of Biomedical Statistics, Academy of Military Medical Sciences, Beijing 100850, China
  • Received:2015-06-15 Revised:2015-10-12 Online:2016-05-28 Published:2018-06-12
  • Contact: 胡良平,Tel:010-66932127;E-mail:lphu812@sina.com E-mail:lphu812@sina.com
  • Supported by:
    胡良平,Tel:010-66932127;E-mail:lphu812@sina.com

摘要: 目的:引起生理学研究人员对样本含量估计重要性的认识。方法:论述样本含量估计的意义及存在的问题,介绍常用的样本含量估计方法以及获取其他样本含量估计方法的途径。结果:清楚地表述了估计样本含量必需明白的基本概念、前提条件,并通过实例给出了两种场合下所需样本含量的估计过程和结果。结论:在估计样本含量时,必须明确资料将选用何种统计分析方法处理,并且应满足有关的前提条件,才能得到正确的估计结果。

关键词: 生理学, 样本含量估计, 成组设计, 两两比较

Abstract: Objective:To bring about physiological researchers' attention of the importance of sample size estimation. Methods:The significance as well as the current problems of sample size estimation were illustrated and the commonly-used sample size estimation methods were introduced. Results:The basic concepts and necessary premises of sample size estimation were stated. The estimation processes and results under two different circumstances were elaborated in detail via examples. Conclusion:To attain the proper estimated sample sizes, the computation must satisfy the necessary premises which included the appropriate statistical analysis methods to be used.

Key words: physiological research, sample size estimation, two-sample parallel design, multiple comparisons

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