肌萎缩侧索硬化患者肌电图F波和束颤波的特点及其相关性*

doi:10.12047/j.cjap.5833.2019.116

中国应用生理学杂志 ›› 2019, Vol. 35 ›› Issue (6): 530-532.doi: 10.12047/j.cjap.5833.2019.116

肌萎缩侧索硬化患者肌电图F波和束颤波的特点及其相关性^*

陈瑛^1,2, 尹厚民¹, 章殷希¹, 丁美萍^1△

1. 浙江大学医学院附属第二医院神经内科, 杭州 310009;
2. 嵊州市人民医院浙江大学附属第一医院嵊州分院神经内科, 嵊州 312400

收稿日期:2019-02-28 出版日期:2019-11-28 发布日期:2020-04-02

Characteristics and correlation of F wave and fasciculation potential in amyotrophic lateral sclerosis

CHEN Ying, YIN Hou-min, ZHANG Yin-xi, DING Mei-ping

Received:2019-02-28 Online:2019-11-28 Published:2020-04-02

摘要/Abstract

摘要： 目的:研究肌萎缩侧索硬化(ALS)患者肌电图检查中异常F波与束颤波的特点及其相关性。方法:收集2016年9月至2018年2月就诊于浙江大学医学院附属第二医院神经内科的54例ALS患者,进行常规肌电图检查和F波测定,记录216条正中神经、胫后神经的F波以及324块肌肉的束颤波相关参数,计算F波出现率、巨大F波、束颤波的出现率及其异常率,分析巨大F波、束颤波与病程的关系以及巨大F波和束颤波之间的关联性。结果:F波出现率的异常率88.89%,巨大F波出现率55.56%,束颤波出现率48.15%;有束颤波的病程与没有束颤波病程比较具有明显差异(P＜0.01),有巨大F波的病程与未出现巨大F波病程比较无明显差异(P＞0.05);上肢正中神经巨大F波出现与束颤波的出现无关联(P＞0.05),下肢胫后神经巨大F波出现与束颤波的出现比较具有相关性(P=0.05)。结论:以上肢为主的F波出现率异常、以下肢为主的巨大F波和束颤波的出现可作为ALS电生理诊断阳性指标。有束颤波或巨大F波时可考虑疾病相对较早,且有较好的神经再支配及代偿,进展相对较慢。

关键词: 肌萎缩侧索硬化, F波, 巨大F波, 束颤波

Key words: amyotrophic lateral sclerosis, F wave, giant F wave, fasciculation potentials

中图分类号:

R7-41

陈瑛, 尹厚民, 章殷希, 丁美萍. 肌萎缩侧索硬化患者肌电图F波和束颤波的特点及其相关性^*[J]. 中国应用生理学杂志, 2019, 35(6): 530-532.

CHEN Ying, YIN Hou-min, ZHANG Yin-xi, DING Mei-ping. Characteristics and correlation of F wave and fasciculation potential in amyotrophic lateral sclerosis[J]. CJAP, 2019, 35(6): 530-532.

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肌萎缩侧索硬化患者肌电图F波和束颤波的特点及其相关性^*

Characteristics and correlation of F wave and fasciculation potential in amyotrophic lateral sclerosis

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