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中国应用生理学杂志 ›› 2018, Vol. 34 ›› Issue (4): 336-339.doi: 10.12047/j.cjap.5607.2018.077

• 研究论文 • 上一篇    下一篇

帕米尔高原慢性高山病患病调查分析

阳盛洪, 李彬, 高亮, 李年华   

  1. 解放军第十八医院 新疆军区高山病研究所, 新疆 叶城 844900
  • 收稿日期:2017-10-30 修回日期:2018-01-18 出版日期:2018-07-28 发布日期:2019-02-21
  • 通讯作者: 李彬 E-mail:newviolet@qq.com
  • 基金资助:
    新疆维吾尔自治区科技支撑计划(201533106)

Prevalence and risk factors of chronic mountain sickness in Pamirs plateau

YANG Sheng-hong, LI Bin, GAO Liang, LI Nian-hua   

  1. Xinjiang Military Command Mountain Sickness Research Institute, Hospital 18 of PLA, Yecheng 844900, China
  • Received:2017-10-30 Revised:2018-01-18 Online:2018-07-28 Published:2019-02-21
  • Supported by:
    新疆维吾尔自治区科技支撑计划(201533106)

摘要: 目的:调查帕米尔高原地区慢性高山病(CMS)患病情况,分析其临床特征及其影响因素。方法:采用青海CMS记分系统,对帕米尔高原地区的824名居民进行CMS症状调查,记录人口学特征、血压(BP)、血氧饱和度(SaO2)、心率和CMS特异症状,抽取静脉血检测血红蛋白(Hb)值。结果:帕米尔高原地区CMS总体患病率为22.08%,其中轻度为21.84%,中度为0.24%,未见重度CMS患者。性别、民族、年龄、居住海拔高度、移居时间、职业、习服方式等是CMS患病的影响因素(P<0.05,P<0.01),分别比较男性和女性的CMS患病率与高原红细胞增多症患病率,差异有统计学意义(χ2=90.59和44.13,P<0.01)。多元线性回归分析显示:年龄、体质指数(BMI)、SaO2和收缩压(SBP)与CMS患病率密切相关(P<0.01)。结论:帕米尔高原地区慢性高原病患病率较高,而高原红细胞增多症并不多见,CMS患病类型以高原衰退为主。合理安排工作和运动,避免过度疲劳;合理吸氧,提高血氧饱和度;积极治疗,控制血压;安排平原休假或疗养等措施有助于改善慢性高原病症状,减少患病率。

关键词: 高原, 慢性高山病, 患病率, 调查

Abstract: Objective: To investigate the prevalence of chronic mountain sickness (CMS) and its predisposing factors in Pamirs plateau and analysis clinical feature and risk factors. Methods: Eight hundred and twenty-four individuals in Pamirs plateau were surveyed used Qinghai CMS scoring system. Demographics, BP, SaO2, heart rate and specified symptoms of CMS were recorded, Hb level was estimated. Results: Overall CMS prevalence was 22.08%, including 21.84% mild and 0.24% moderate without severe patient. Gender, nation, age, immigration time, altitude, occupation and accommodation mode were risk factors for CMS (P<0.05 or P<0.01), CMS prevalence was higher than HAPC rate both in male and female (χ2=90.59 and 44.13, P<0.01). Multiple linear regression analysis showed age, BMI, SaO2 and systolic pressure correlated with CMS (P<0.01). Conclusion: Chronic mountain sickness prevalence in Pamirs plateau is rather high but high altitude polycythemia prevalence is low, so the disease type is high altitude deterioration. Work and exercise more reasonable to avoid overtiredness, oxygen inhalation to raise blood oxygen saturation, control blood pressure and resting therapy can improve CMS symptom and decrease prevalence.

Key words: high altitude, chronic mountain sickness, prevalence, survey

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