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CJAP ›› 2021, Vol. 37 ›› Issue (2): 113-119.doi: 10.12047/j.cjap.0083.2021.113

• ORIGINAL ARTICLES •     Next Articles

Effect of different work rate increasing rate on the overall function evaluation of cardiopulmonary exercise testing I—peak parameters and changes in respiratory exchange rate

HAO Lu1,2, SUN Xing-guo1,3△, SONG Ya1,3, LIU Fang1, TAI Wen-qi1, GE Wan-gang1, LI Hao1, ZHANG Ye, CHEN Rong, 1, ZOU Yu-xin, 1,5, MA Ming-xin, 1,4, XIA Rui, 1, HUANG Yan1,4, XIE You-hong3   

  1. 1. Fuwai Hospital,Chinese Academy of Medical Sciences/National Center for Cardiovascular Diseases/ State Key Laboratory of Cardiovascular Diseases/Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing 100037;
    2. Henan Provincial People's Hospital,Henan 450003;
    3. The Affiliated Rehabilitation Hospital of Chongqing Medical University, Chongqing 400050;
    4. Dalian Children's Hospital,Dalian 116000;
    5. Liaocheng People's Hospital, Liaocheng 252000, China
  • Received:2020-08-12 Revised:2021-03-15 Online:2021-03-28 Published:2021-10-20

Abstract: Objective: To observe the effect of healthy volunteers different work rate increasing rate cardiopulmonary exercise test (CPET) on the peak exercise core indicators and the changes of respiratory exchange rate (RER) during exercise, to explore the effect of different work rate increasing rate on CPET peak exercise related indicators. Methods: Twelve healthy volunteers were randomly assigned to a moderate (30 W/min), a relatively low (10 W/min) and relatively high (60 W/min) three different work rate increasing rate CPET on different working days in a week. The main peak exercise core indicators of CPET data: VO2, VCO2, work rate (WR), breathe frequency(Bf), tidal volume (VT), ventilation (VE), heart rate (HR), blood pressure (BP), Oxygen pulse(O2P), exercise time and RER for each period of CPET were analyzed using standard methods. The ANOVA test and paired two-two comparison was performed on the difference of each index in the three groups of different work rate increasing rate. Results: Compared with the moderate work rate group, the peak work rate of the lower and higher work rate groups were relatively lower and higher, respectively ((162.04±41.59) W/min vs (132.92±34.55) W/min vs (197.42±46.14) W/min, P<0.01); exercise time was significantly prolonged and shortened ((5.69 ± 1.33) min vs (13.49 ± 3.43) min vs (3.56 ± 0.76) min, P<0.01); peak RER (1.27 ± 0.07 vs 1.18 ± 0.06 vs 1.33 ± 0.08, P<0.01~P<0.05) and the recovery RER maximum (1.72±0.16 vs 1.61±0.11 vs 1.81±0.14, P<0.01~P<0.05) were significantly decreased and increased. Conclusion: Different work rate increasing rate of CPET significantly change the Peak Work Rate, exercise time, Peak RER, and maximum RER during recovery. The CPET operator should choose an individualized work rate increasing rate that is appropriate for the subject, and also does not use a fixed RER value as a basis for ensuring safety, the subject's extreme exercise, and early termination of exercise.

Key words: respiratory exchange rate, cardiopulmonary exercise testing, work rate increasing rate, stop exercise standard, safety and risk

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