Meta-analysis on influence of different exercise intervention modes to blood glucose related indexes of pre-diabetes

doi:10.12047/j.cjap.5400.2017.048

Abstract

Abstract: Objective: To assess the influence of the different exercise intervention mode, aerobic exercise training(AET), resistance training(RT) and AET RT, on blood glucose of pre-diabetes. Methods: Literatures were identified from the PubMed, EMBASE, EBSCO, CNKI and Wanfang databases. Relevant journals or conference proceedings were also searched manually. The qualities of randomized con-trolled trials that conformed to inclusion criteria were evaluated. Meta-analysis of the obtained related data was completed utilizing RevMan 5.2 statistical software. Mean difference of index related in exercise intervention groups and control group were calculated across the studies. Results: Eight original literatures enrolled in this study. Compared with control group, combined effect of different exercise interventions on fast-ing blood glucose showed no significant, consistent with different intervention subgroups analysis. RT group and AET + RT group showed a sig-nificantly reduced role on 2 h postprandial blood index (P < 0.05). AET group showed a significantly reduced role on insulin resistance in-dex. Conclusion: To pre-diabetic, effects of exercise on postprandial 2 h blood glucose and insulin resistance index are related to modes of ex-ercise. Effects of exercise on fasting blood glucose, but still could not be determined.

Key words: pre-diabetes, exercise intervention, indexes of blood glucose, Meta-analysis

JIANG Ji-quan, XIA Xiao-hui, WANG Hui, ZHANG Zu-hua. Meta-analysis on influence of different exercise intervention modes to blood glucose related indexes of pre-diabetes[J]. CJAP, 2017, 33(2): 189-192.

References

[1] Garnett SP, Gow M, Ho M, et al. Optimal macronutrient content of the diet for,adolescents with prediabetes; RESIST a randomised control trial[J]. J Clin Endocrinol Metab, 2013, 98(5):2116-2125.
[2] Aizawa K, Shoemaker JK, Overend TJ, et al. Effects of lifestyle modification on central artery stiffness in metabolic syndrome subjects with pre-hypertension and/or pre-diabetes[J]. Diabetes Res Clin Pract, 2009, 83(2):249-256.
[3] Aldana S, Barlow M, Smith R, et al. A worksite diabetes prevention program:two-year impact on employee health[J]. AAOHN J, 2006, 54(9):389-395.
[4] 智永红. 运动对老年人糖代谢异常的调节作用[J]. 中国老年学杂志, 2014, 34(23):6578-6580.
[5] Cha E, Kim KH, Umpierrez G, et al. A feasibility study to develop a diabetes prevention program for young adults with prediabetes by using digital platforms and a handheld device[J]. Diabetes Educ, 2014, 40(5):626-637.
[6] Savoye M, Caprio S, Dziura J, et al. Reversal of early ab-normalities in glucose metabolism in obese youth:results of an intensive lifestyle randomized controlled trial[J]. Diabetes Care, 2014, 37(2):317-324.
[7] Eriksson KF, Lindgarde F. Prevention of type 2(non-insulin-dependent) diabetes mellitus by diet and physical exercise. The 6-year Malmo feasibility study[J]. Diabetologia, 1991, 34(12):891-898.
[8] Maji D, Roy RU, Das S. Prevention of type 2diabetes in the prediabetic population[J]. J Indian Med Assoc, 2005, 103(11):609-611.
[9] Solomon TP, Haus JM, Kelly KR, et al. A low-glycemic in-dex diet combined with exercise reduces insulin resistance, postprandial hyperinsulinemia, and glucose-dependent in-sulinotropic polypeptide responses in obese, prediabetic hu-mans[J]. Am J Clin Nutr, 2010, 92(6):1359-1368.
[10] Pedersen LR, Olsen RH, Jurs A, et al. A randomized trial comparing the effect of weight loss and exercise training on insulin sensitivity and glucose metabolism in coronary artery disease[J]. Metabolism, 2015, 64(10):1298-1307.
[11] Straczkowski M, Kowalska I, Dzienis-Straczkowska S, et al. Changes in tumor necrosis factor-alpha system and insulin sensitivity during an exercise training program in obese women with normal and impaired glucose tolerance[J]. Eur J En-docrinol, 2001, 145(3):273-280.
[12] Jenkins NT, Hagberg JM. Aerobic training effects on glucose tolerance in prediabetic and normoglycemic humans[J]. Med Sci Sports Exerc, 2011, 43(12):2231-2240.
[13] Geirsdottir OG, Arnarson A, Briem K, et al. Effect of 12-week resistance exercise program on body composition, mus-cle strength, physical function, and glucose metabolism in healthy, insulin-resistant, and diabetic elderly Icelanders[J]. J Gerontol A Biol Sci Med Sci, 2012, 67(11):1259-1265.
[14] Jenkins NT, Hagberg JM. Aerobic training effects on glucose tolerance in prediabetic and normoglycemic humans[J]. Med Sci Sports Exerc, 2011, 43(12):2231-2240.
[15] Marinik EL, Kelleher S, Savla J, et al. The Resist Diabetes trial:Rationale, design, and methods of a hybrid efficacy/effectiveness intervention trial for resistance training mainte-nance to improve glucose homeostasis in older prediabetic adults[J]. Contemp Clin Trials, 2014, 37(1):19-32.
[16] Malin SK, Solomon TP, Blaszczak A, et al. Pancreatic be-ta-cell function increases in a linear dose-response manner fo llowing exercise training in adults with prediabetes[J]. Am J Physiol Endocrinol Metab, 2013, 305(10):E1248-1254.
[17] Eriksson J, Tuominen J, Valle T, et al. Aerobic endurance exercise or circuit-type resistance training for individuals with impaired glucose tolerance,[J]. Horm Metab Res, 1998, 30(1):37-41.
[18] Burtscher M, Gatterer H, Kunczicky H, et al. Supervised exercise in patients with impaired fasting glucose:impact on exercise capacity[J]. Clin J Sport Med, 2009, 19(5):394-398.
[19] 刘一平, 王志红, 李健卫, 等. 不同运动对糖耐量减低者肱动脉内皮功能、胰岛素敏感性的影响[J]. 福建师范大学学报(自然科学版), 2012, 28(3):113-118.
[20] Alvarez C, Ramirez R, Flores M, et al. Effect of sprint in-terval training and resistance exercise on metabolic markers in overweight women[J]. Rev Med Chil, 2012, 140(10):1289-1296.
[21] Malin SK, Gerber R, Chipkin SR, et al. Independent and combined effects of exercise training and metformin on insulin sensitivity in individuals with prediabetes[J]. Diabetes Care, 2012, 35(1):131-136.
[22] 王正珍, 王艳. 有氧运动对糖尿病前期人群胰岛素敏感性的影响[J]. 成都体育学院学报, 2013, 39(9):1-8.
[23] Fritz T, Caidahl K, Krook A, et al. Effects of Nordic walk-ing on cardiovascular risk factors in overweight individuals with type 2diabetes, impaired or normal glucose tolerance[J]. Diabetes Metab Res Rev, 2013, 29(1):25-32.
[24] 罗曦娟, 王正珍, 朱玲, 等. 有氧和抗阻运动对糖尿病前期人群血糖干预效果的比较研究[J]. 中国运动医学杂志, 2015, 34(9):831-837.
[25] 李琳, 唐建平, 范惠芸, 等. 生活方式改变对糖尿病前期人群血糖及相关指标的Meta分析[J]. 中国糖尿病杂志, 2014, 22(6):517-525.