Effects of 16 week aerobic exercise on baPWV and ABI of middle-aged and elderly patients

doi:10.12047/j.cjap.5577.2018.036

Abstract

Abstract: Objective:To investigate the interventional effects of 16-week aerobic exercises on the elderly's arteriosclerosis and its mechanism. Methods:Twenty-seven elderly people with the average age of 62. 70 ±3. 26 joined a 16-week square dance/taijiquan exercise program that conducted 60 minutes each time, six times per week. Arterial stiffness and its related indexes such as systolic pressure(SBP), diastolic pressure(DBP), left brachial-ankle pulse wave velocity (L-baPWV), right brachial-ankle pulse wave velocity(R-baPWV), left ankle brachial index (L-ABI), right ankle brachial index(R-ABI), serum triglyceride(TG), total cholesterol(TC), high density lipoprotein cholesterol(HDL-c), low density lipoprotein cholesterol(LDL-c), superoxide dismutase(SOD), malondialdehyde(MDA) and glutathione peroxidase (GSH-Px) were detected at 3 time points including before exercise program, by the end of exercise for 8 weeks and 16 weeks. Results:① Compared with pre-exercise, the R-baPWV and R-ABI of the elderly people were decreased at the end of the 8^th week, and the L-baPWV, RbaPWV, R-ABI and L-ABI were decreased significantly at the end of the 16^th week. ②Compared with pre-exercise, SBP and DBP were declined markedly (P<0.01, P<0.05) at the end of the 8^th week, SBP, DBP and pulse pressure were decreased significantly (P<0.01, P<0.05) at the end of the 16^th week. ③Compared with pre-exercise, TC and LDL-c were declined markedly (P<0.01) at the end of the 8^th and the 16^th week, and there was no difference of the level of TG and LDL-c between pre-exercise and post-exercise. ④There was no evident difference of serum level of SOD, GSH-Px, MDA between pre-exercise and post-exercise at the end of the 8^th week. Compared with pre-exercise, the level of serum SOD, GSH-Px was increased evidently while the content of serum MDA was decreased significantly (P<0.01). Conclusion:Sixteen-week aerobic exercises could reduce baPWV and ABI levels, regulate blood pressure, blood lipids and lipid peroxides levels of the elderly evidently, thus improve the controlling quality of atherosclerosis.

Key words: aerobic exercise, blood pressure, blood lipids, brachial-ankle pulse wave velocity, ankle brachial index

LI Ning-chuan, YIN Xia-lian, WEI Xiu-xia, LU Wei, SHEN Shi-wen, XIAO Lang, HU Yu-long. Effects of 16 week aerobic exercise on baPWV and ABI of middle-aged and elderly patients[J]. CJAP, 2018, 34(2): 145-149.

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