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CJAP ›› 2017, Vol. 33 ›› Issue (6): 526-530.doi: 10.12047/j.cjap.5601.2017.125

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The relationship between high-sensitivity C-reactive protein (hsCRP) levels and atrial fibrillation early recurrence after paroxysmal atrial fibrillation radiofrequency catheter ablation

ZHAO Yue-xiang1, SHAN Zhao-liang2, GUO Hong-yang2, LIN Kun2, GUO Jian-ping2, WANG Yu-tang1   

  1. 1. Department of Cardiology, Nanlou Clinal Division of PLA General Hospital, Beijing 100853, China;
    2. Department of Cardiovascular Medicine of PLA General Hospital, Beijing 100853, China
  • Received:2017-04-10 Revised:2017-10-14 Online:2017-11-28 Published:2018-06-19
  • Contact: 王玉堂,Tel:010-66876291;E-mail:wvt301@sina.com E-mail:wvt301@sina.com
  • Supported by:
    军队保健专项课题(11BJZ10)

Abstract: Objective: To prospectively clarify the predictive value of high-sensitivity C-reactive protein (hsCRP) on the risk for recurrent atrial arrhythmia in paroxysmal atrial fibrillation (PAF) population who accepted radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF).Methods: There were 57 consecutive patients (53.32±9.98 years; 42 males) with drug-refractory PAF who underwent RFCA were included. Plasma levels of hsCRP and high-sensitivity cardiac troponin T (hs-cTnT) were measured on admission and first five days after RFCA. Twenty-five patients (43.86%) had early recurrence of atrial fibrillation (ERAF).Results: Compared to patients without ERAF (no-AF-recurrence group), baseline hsCRP levels had no significant difference in patients with ERAF (AF recurrence group). There were no significant differences in the peak hsCRP and hs-cTnT levels between no-AF-recurrence group and AF recurrence group. However, change of hsCRP level was significantly correlated with change in hs-cTnT level in patients undergoing RFCA (r=0.268, P=0.044).Conclusion: Among those AF patients undergoing ablation, change of hsCRP level could be for the myocardial injury related to RFCA procedure, which may not be a risk factor to predict ERAF. The variety of hsCRP level may be related to the degree of myocardial injury induced by RFCA.

Key words: atrial fibrillation, high-sensitivity C-reactive protein (hsCRP), circumferential pulmonary vein isolation (CPVI), early recurrence

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