Evidence of waveform information in arterial blood gas by beat-by-beat sampling method in patients with normal heart function

doi:10.12047/j.cjap.0110.2015.005

Abstract

Abstract: Objective: Since 2011 EB-APS conference, we hypotheses that phase switching of inspiration-expiration is dominantly initiated by oscillatory information PaO₂, PaCO₂ and [H⁺] via fast peripheral chemical receptors. However, the evidence of the waveform of ABG is lack. Methods: Six surgery patients with normal heart function and negative Allen test, had been placed the arterial catheterization directly connected to 3×1 000 mm pre-heparin plastic pipe for continuous collecting arterial blood. We counted the number of heart beat for the blood collecting time, and separated the blood pipe into the heart beat numbers' short pieces using haemostatic forceps, then put pipe into iced water at once fir analyzing PaO₂, PaCO₂, pH and SaO₂ as soon as possible. We selected two breaths cycles of waveform from each patient for data calculations of magnitudes and time interval. Results: The heart beat numbers for filling blood into pipe were 16±2, and all covered more than 2 breathing cycles. Each breathing cycle is cover 5±0.6 heart beat. There were significant changes of PaO₂, PaCO₂, [H⁺]a and SaO₂ ( i.e. the highest high values compare to the next lowest values, P<0.05). The time interval of changing PaO₂, PaCO₂, [H⁺]a and SaO₂magnitudes were 11.28±1.13 mmHg,1.77±0.89 mmHg,1.14±0.35 nmol/L and 0.52%±0.44% respectively. Conclusion: This simple continuous beat-by-beat arterial blood sampling and ABG analyzing method is new and practicable. We obtain a clear evidence of periodic parameters ABG waveform, which following breathing cycle.

Key words: ABG, PaO₂, PaCO₂, pHa, SaO2, beat-by-beat arterial blood sampling, periodic breathing, control and regulation of breathing

CLC Number:

R33-3

SUN Xing-guo, YAO You-xiu, LI Jun, WANG Gu-yan, ZHANG Hong-liang, TAN Xiao-yue, LIU Fang, CI Zheng, HU Sheng-shou. Evidence of waveform information in arterial blood gas by beat-by-beat sampling method in patients with normal heart function[J]. CJAP, 2015, 31(4): 316-321.

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