The relationship between high-sensitivity C-reactive protein (hsCRP) levels and atrial fibrillation early recurrence after paroxysmal atrial fibrillation radiofrequency catheter ablation

doi:10.12047/j.cjap.5601.2017.125

Abstract

Abstract: Objective: To prospectively clarify the predictive value of high-sensitivity C-reactive protein (hsCRP) on the risk for recurrent atrial arrhythmia in paroxysmal atrial fibrillation (PAF) population who accepted radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF).Methods: There were 57 consecutive patients (53.32±9.98 years; 42 males) with drug-refractory PAF who underwent RFCA were included. Plasma levels of hsCRP and high-sensitivity cardiac troponin T (hs-cTnT) were measured on admission and first five days after RFCA. Twenty-five patients (43.86%) had early recurrence of atrial fibrillation (ERAF).Results: Compared to patients without ERAF (no-AF-recurrence group), baseline hsCRP levels had no significant difference in patients with ERAF (AF recurrence group). There were no significant differences in the peak hsCRP and hs-cTnT levels between no-AF-recurrence group and AF recurrence group. However, change of hsCRP level was significantly correlated with change in hs-cTnT level in patients undergoing RFCA (r=0.268, P=0.044).Conclusion: Among those AF patients undergoing ablation, change of hsCRP level could be for the myocardial injury related to RFCA procedure, which may not be a risk factor to predict ERAF. The variety of hsCRP level may be related to the degree of myocardial injury induced by RFCA.

Key words: atrial fibrillation, high-sensitivity C-reactive protein (hsCRP), circumferential pulmonary vein isolation (CPVI), early recurrence

ZHAO Yue-xiang, SHAN Zhao-liang, GUO Hong-yang, LIN Kun, GUO Jian-ping, WANG Yu-tang. The relationship between high-sensitivity C-reactive protein (hsCRP) levels and atrial fibrillation early recurrence after paroxysmal atrial fibrillation radiofrequency catheter ablation[J]. CJAP, 2017, 33(6): 526-530.

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