急性肺损伤/急性呼吸窘迫综合征致肺水肿的病理生理研究进展

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摘要急性肺损伤/急性呼吸窘迫综合征(ALI/ARDS)是血管内液渗透到肺间质和肺泡内，引起大量肺水形成高通透性水肿所致。肺水肿形成是其重要的病理生理改变。文章根据近年病理生理进展，从效应细胞的反应失调，凝血-纤溶系统改变，炎症反应机制等方面进行综述，以期为进一步研究提供参考。

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关键词 ：急性肺损伤/急性呼吸窘迫综合征, 肺水肿, 效应细胞, 凝血-纤溶系统, 炎性反应

Abstract：Acute lung injury / acute respiratory distress syndrome (ALI/ARDS) is a result of intravascular fluid penetration into the pulmonary interstitial and alveolar, causing a large amount of high permeability pulmonary edema. Pulmonary edema formation is an important pathological and pathophysiological change in the ALI/ARDS. In this paper, researches on pathogenesis of pulmonary edema induced by ALI/ARDS were reviewed according to the recent progress in pathophysiology, involving the function disorders of effector cells, the changes of the coagulation fibrinolysis system and the mechanisms of inflammatory reaction. This paper is expected to provide reference for further research.

Key words： acute lung injury / acute respiratory distress syndrome pulmonary edema effector cells coagulation fibrinolysis system inflammatory reaction

出版日期: 2016-09-14

作者简介: 潘蔚(1970-)，男，大学本科，主治医师。从事急救医学工作。

引用本文:

潘蔚，刘军生，刘润生，李杨. 急性肺损伤/急性呼吸窘迫综合征致肺水肿的病理生理研究进展[J]. 解放军预防医学杂志, 2016, 34(4): 576-579.
PAN Wei , LIU Junsheng, LIU Runsheng, LI Yang. Research Progress in Pathogenesis and Physiology of Pulmonary Edema Induced by Acute Lung Injury and Acute Respiratory Distress Syndrome. Journal of Preventive Medicine of Chinese People's Liberation Army, 2016, 34(4): 576-579.

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http://manu37.magtech.com.cn/Jwk_jsyxkx/jfj/CN/ 或 http://manu37.magtech.com.cn/Jwk_jsyxkx/jfj/CN/Y2016/V34/I4/576

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