Abstract：Epigenetics is defined as heritable changes in gene activity and expression that occur without alteration in DNA sequences and are sufficiently powerful to regulate the dynamics of gene expression. Epigenetic regulation includes DNA methylation, histone modification, and noncoding RNA regulation. Epigenetic modifications play an important role in the biological growth, development and the etiology of disease. Quercetin, a natural pytochemical, is widely present in fruits and vegetables. Increasing reasearch has indicated that quercetin has very important effects on epigenics. In the present paper, the progress of quercetin in gene methylation, histone acetylation, microRNA aberrant expressions was summarized, and a new mechanism of quercetin in epigenetics was introduced.
蒲玲玲, 冯建, 高蔚娜, 郭长江. 槲皮素健康效应的表观遗传学机制研究进展[J]. 解放军预防医学杂志, 2016, 34(5): 748-750.
PU Lingling, FENG Jian, GAO Weina, GUO Changjiang. Epigenetic Mechanisms of Quercetin on Health. Journal of Preventive Medicine of Chinese People's Liberation Army, 2016, 34(5): 748-750.
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