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The HBsAb Level of Soldiers in Guangzhou Military Unitsand its Effect of Hepatitis B Vaccine |
SU Jianxin, LI Xi, XIE Xiaobo, HONG Wenyan, YU Dexian, ZHOU Shiming, LIU Jianwei, LIU Lebin* |
Department of Disease Surveillance and Control, Center for Disease Control and Prevention of Guangzhou Military Region, Guangzhou 510507, China |
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Abstract Objective To investigate the HBsAb level of soldiers in Guangzhou military region and to evaluate the effect of hepatitis B vaccine, so as to provide the reference for hepatitis B prevention and treatment.Methods A total of 1185 soldiers with vaccination were randomly sampled from three units in Guangdong, their blood samples (5 ml per one) were got and detected by ELISA method for HBsAb level. At the same time, 890 blood samples from new recruits without vaccination in 2013 were also detected as control.Results The HBsAb positive rate of the 1185 soldiers was 81.8% (969/1185), the substandard of HBsAb level accounted for 15.1% (179/1185). The HBsAb positive rate of the 890 recruits without vaccination in 2013 was 63.9% (569/890), the substandard of HBsAb level accounted for 23.6% (210/890). The HBsAb positive rate (81.8%) and qualified rate (66.7%) of sampled soldiers were significantly higher than those of the 890 new recruits without vaccination (63.9%, 40.3%, respectively) (P<0.01).Conclusions HBsAb level can be used to evaluate the effect of hepatitis B vaccine and to find the question in hepatitis B prevention.
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Published: 30 August 2016
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