7种有机磷农药对不同来源乙酰胆碱酯酶活性的抑制作用比较

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Abstract Objective To study the sensitvity of seven types of organophosphorus pesticides to acetylcholinesterase(AChE) from different sources.Methods We detected the acetylcholinesterase (AChE) activity of electric organs of numbfish and Musca domestica to seven types of organophosphorus pesticides (fethion, glyphosate, parathion, chlorpyrifos, moncrotophos, malathion, phorate) .Results The result showed that the AChE activity of Musca domestica to fethion, glyphosate, parathion, chlorpyrifos and moncrotophos was higher than that of numbfish.The highest inhibition rates were 85.14%、75.28%、40.94%、and 85.43% respectively at 1000μg/L concentration.However, the AChE activity of numbfish to malathion and phorate was higher than that of Musca domestica, and the highest inhibition rates were 45.29%、80.58% respectively at the concentration of 1000μg/L.Conclusion The AChE of Musca domestica is much more sensitive to fethion, glyphosate, parathion, chlorpyrifos and moncrotophos while the AChE of electric organs of numbfish is much more sensitive to malathion and phorate.

Key words： organophosphorus pesticides acetylcholinesterase(AChE) activity inhibition numbfish and Musca domestica

Received: 24 April 2015 Published: 05 January 2017

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http://manu37.magtech.com.cn/Jwk_jsyxkx/jfj/EN/ OR http://manu37.magtech.com.cn/Jwk_jsyxkx/jfj/EN/Y2016/V34/I6/846

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