血液灌流对老年急性重度有机磷中毒患者脏器的保护作用

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Abstract Objective To investigate the protective effect of hemoperfusion in senile patients with severe acute organophosphorus pesticide poisoning.Methods 120 elderly patients diagnosed with severe organophosphate poisoning according were evenly and randomlydivided into blood perfusion group (perfusion group) and conventional drug treatment group (control group). The changes of Crs-C,AST,ALT,CK-MB,cTnI,BNP,NSE,PT,APTT and Scr were compared between the two groups. Results Two hours after admission,there was no significant difference (P>0.05)in levels of Crs-C,AST,ALT,CK - MB,cTnI,BNP,NSE,PT and APT between the two groups of patients. After three days of treatment,the levels ofScr,Crs-C,AST,ALT,CK-MB,cTnI,BNP,NSE,PT,and APTT in hemoperfusion group were lower than in control group (P<0.05). Conclusion Hemoperfusion can reduce the damange of organophosphate poisoning to the heart, liver, kidney and brain of patients,alleviate abnormalities of the blood coagulation system and protect organs from secondary damage.

Key words： blood perfusion organic phosphorus poisoning severe secondary injury

Received: 22 February 2016 Published: 05 January 2017

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	Articles by authors
	XIE Zhuoyang
	RONG Guangcheng
	WANG Liming

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XIE Zhuoyang,RONG Guangcheng,WANG Liming. Protection Efficacy of Hemoperfusion for Elderly Patients with Acute Severe Organophosphorus Poisoning[J]. Journal of Preventive Medicine of Chinese People's Liberation Army, 2016, 34(6): 849-850.

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http://manu37.magtech.com.cn/Jwk_jsyxkx/jfj/EN/ OR http://manu37.magtech.com.cn/Jwk_jsyxkx/jfj/EN/Y2016/V34/I6/849

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