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Acoustic Radiation Force Impulse in Diagnosis of Bi-Rads 4 Breast Lesions |
YOU Qiqin, WU Rong |
Deportment of Ultrasound, Shanghai Tenth People's Hospital,Tongji University, Shanghai 200072,China |
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Abstract Objective To observe the value of the acoustic radiation force impulse (ARFI) as a new method to differentiate malignant BI-RADS 4 breast lesions from benign ones.Methods A total of 292 patients with 311 breast lesions were enrolled into the study after selection. The breast lesions were examined by conventional ultrasound (US).The SWV value of these lesions was determined by virtual touch tissue quantification (VTQ), and these lesions were classified usingvirtual touch tissue imagine (VTI). Then, the SWV value and VTI were used to correct the classification of BI-RADS 4. With the pathological results as the final diagnosis,the receiver-operating characteristic curve (ROC) was drawn to evaluate the diagnostic value of SWV before and after BI-RADS 4 correction by comparing the AUC of the respective ROC curve. Results Before correction, the sensitivity, specificity, AUC of ROC curve to BI-RADS 4 breast lesions were 85%, 79.6% and 0.854, respectively, while the 95% confidence interval was 80.7%~90%. The score 4 of VTI and 4.97m/s of SWV were accepted as the optimal cut-off value and to diagnose benign breast lesions from malignant ones. After correction, the sensitivity, specificity, AUC of ROC curve to BI-RADS 4 breast lesions were 89.2%, 85.9% and 0.939, respectively, while the 95% confidence interval was 91.3%~96.5%. The difference in AUC of the respective ROC curve was statistically significant(z=5.57,P<0.01). Conclusion ARFI elastography can effectively improve the accuracy with which benign BI-RADS 4 breast lesions are distinguished from malignant ones.
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Received: 17 March 2016
Published: 05 January 2017
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[1] |
张露,周平,邓金,等.常规超声、压迫式弹性成像及声脉冲辐射力成像鉴别诊断良恶性乳腺肿瘤的对比研究[J].中南大学学报医学版,2014,39(12):1246.
|
[2] |
张磊.声脉冲辐射力弹性成像技术评价乳腺癌新辅助化疗疗效的初步研究[J].天津医科大学,2014(4):260.
|
[3] |
OPHIR J,CESPEDES I,PONNEKANTI H,et al.Elastrography:A quantitative method for imaging the elasticity of biological tissues[J].Ultrason Imaging,1991,13(2):111.
|
[4] |
TOZAKI M,SAITO M,JOO C,et al.Ultrasonographic tissue quantification of the breast using acoustic radiation force impulse technology:phantom study and clinical application[J].Jpn Radiol,2011,29(8):598.
|
[5] |
American College of Radiology.Breast imaging reporting and data system(BI-RADS):ultrasound[M].Reston VA:American College of Radiology,2003:1-81.
|
[6] |
周学武,王文慧,叶海莉.乳腺血氧功能成像技术原理及临床应用[J].医疗卫生装备,2014,35(8):137.
|
[7] |
王艳艳,赵跃华,张红,等.声脉冲辐射力成像技术在乳腺良恶性肿块鉴别中的应用[J].齐齐哈尔医学院学报,2014(16):2368.
|
[8] |
李文雪,朱家安,刘芳,等.声脉冲辐射力成像对正常跟腱弹性特征的评估[J].中国超声医学杂志,2015,31(8):742.
|
[9] |
NIGHTINGALE K,SOO M S,NIGHTINGALE R,et al.Acoustic radiation force imrulse imaging: In vivo demonstration of clinical feasibility[J].Ultrasound Med Biol,2002,28(2):227.
|
[10] |
单叔煤,徐敏,王玉成,等.乳腺良恶性肿瘤中彩色多普勒血流成像与超声弹性成像的诊断价值[J].医疗卫生装备,2015,36(12):80.
|
[11] |
吴芳,崔凤荣,芦桂林,等.声脉冲辐射成像技术对乳腺肿块鉴别诊断的临床研究[J].农垦医学,2014(2):101.
|
[12] |
林梅影,金占强.声脉冲辐射力成像技术鉴别诊断BI-RADS 4类病灶[J].中国医学影像技术,2014,30(6):872.
|
[13] |
王晓慧,郑春梅.声脉冲辐射力成像技术在乳腺肿瘤诊断中的应用价值[J].黑龙江医药科学,2013,36(4):109.
|
[14] |
MELODELYNA D,BAMBER J,DUCK FA,et al.Elastography for breast cancer diagnosis using radiation fiorce : system developm ent and perform ance evaluation[J].Ultrasound Med Biol,2006,32(3):387.
|
[15] |
王芳,红华,李敏,等.ARFI技术结合BI-RADS诊断标准对乳腺良恶性肿瘤的诊断价值[J].内蒙古医科大学学报,2015(2):122.
|
[16] |
张磊,陈东风,王丽娟,等.声脉冲辐射力弹性成像技术评价乳腺癌新辅助化疗疗效的初步探讨[J].济宁医学院学报,2014,37(4):260.
|
[17] |
李玉林.病理学[M].6版.北京:人民卫生出版社,2004:318-319.
|
[18] |
FRIEDRICH-RUST M, WUNDER K, KRIENER S,et al.Liver fibrosis in viral hepatitis:noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography[J]. Radiology,2009,252(252):595.
|
[19] |
姚明华,吴蓉,马方,等.声触诊组织定量技术对不同大小乳腺实性肿块的诊断价值研究[J].中华临床医师杂志,2013,7(12):5355.
|
[20] |
杨琳,马方,刘媛媛,等.超声弹性成像对乳腺实质性肿瘤定性诊断价值[J].同济大学报:医学版,2008,29(5):135.
|
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