SUGAR-SWEETENED BEVERAGES CONSUMPTION AND THE RISK OF DEPRESSION: A META-ANALYSIS OF PROSPECTIVE COHORT STUDIES

XIE Yi-sha, HUAN Dong-xiang, MA Jie-yu, LUAN Wen-xue, SHANG Si-yuan, LI Xin-li

Acta Nutrimenta Sinica ›› 2024, Vol. 46 ›› Issue (2) : 183-191.

Acta Nutrimenta Sinica ›› 2024, Vol. 46 ›› Issue (2) : 183-191.
CRITICAL REVIEWS

SUGAR-SWEETENED BEVERAGES CONSUMPTION AND THE RISK OF DEPRESSION: A META-ANALYSIS OF PROSPECTIVE COHORT STUDIES

  • XIE Yi-sha, HUAN Dong-xiang, MA Jie-yu, LUAN Wen-xue, SHANG Si-yuan, LI Xin-li
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Abstract

Objective Published studies have drawn inconsistent conclusions on the association between sugar-sweetened beverages (SSBs) consumption and the risk of depression. Therefore, we conducted a meta-analysis to further evaluate the relationship between SSBs intake and the risk of depression. Methods Literatures related to prospective cohort studies reporting the association between SSBs consumption and the risk of depression were searched from PubMed, Web of Science, Embase, Cochrane, CNKI and Wanfang database up to March 1, 2023. Heterogeneity testing was performed by DerSimonian-Laird method. Random-effected model was used to calculate the pooled risk estimate, and the causes of heterogeneity were found by subgroup analysis and sensitivity analysis. Publication bias was assessed by funnel plot and Egger test, and the impact on the results was evaluated by Duval and Tweedie nonparametric trim and fill method. Results A total of 7 cohort studies with 294,910 participants were included in the present meta-analysis. The results indicated that the combined risk of depression was 1.28 (95% CI: 1.08-1.51) in the group with the highest SSBs intake compared to the lowest group. The results of subgroup analysis showed significant differences in the associations between SSBs consumption and depression risk by sex, age, location, and duration of follow-up. Sensitivity analysis didn’t support the excessive impact of the included study on the combined effects of SSBs consumption and depression risk. Conclusion Excessive consumption of SSBs endows higher risk of depression, but further confirmation is needed.

Key words

sugar-sweetened beverages (SSBs) / depression risk / prospective cohort study / Meta-analysis

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XIE Yi-sha, HUAN Dong-xiang, MA Jie-yu, LUAN Wen-xue, SHANG Si-yuan, LI Xin-li. SUGAR-SWEETENED BEVERAGES CONSUMPTION AND THE RISK OF DEPRESSION: A META-ANALYSIS OF PROSPECTIVE COHORT STUDIES[J]. Acta Nutrimenta Sinica. 2024, 46(2): 183-191

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