EFFECTS OF BRAZILIAN GREEN PROPOLIS ON SERUM BIOCHEMICAL AND IMMUNO-INFLAMMATORY PARAMETERS IN THE ELDERLY

GAO Wei-na; WEI Jing-yu; WU Jian-quan; PU Ling-ling; GUO Chang-jiang

Acta Nutrimenta Sinica ›› 2024, Vol. 46 ›› Issue (5) : 457-461.

ORIGINAL ARTICLES

GAO Wei-na, WEI Jing-yu, WU Jian-quan, PU Ling-ling, GUO Chang-jiang

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Abstract

Objective To investigated effects of Brazilian green propolis on serum glucose, lipids, proteins, antibodies and inflammatory factors in the elderly. Methods A total of thirty-two residents aged over 60 years were recruited from a community of Tianjin. They signed informed consent and took 4 propolis soft capsules (0.5g per capsule) daily. The capsules were taken after meal, 2 capsules per time and two times per day. The intervention time lasted for 12 weeks. Elbow venous blood was collected at baseline, 6w and 12w, respectively. The levels of fasting serum glucose, proteins, lipids, antibodies (IgA, IgG and IgM) and cytokines (Il-4, Il-1β and INF-γ) were detected by commercial kits. Dietary survey was conducted using a 24-hour dietary recall method. Results At the end of experiment, the fasting serum glucose level was significantly lower than that at baseline or 6 weeks (P<0.05). The serum IgG level at 6 w was significantly higher than that at baseline, and the 12 w level was notably lower than the 6w level (P<0.05). There was no significant difference between 12w and baseline in the serum IgG level (P<0.05). The serum IgA levels at 6 w and 12 w were remarkably lower than the level at baseline (P<0.05). Brazilian green propolis had little effect on serum lipid, proteins, IgM and cytokines in aged people. The results of the two dietary surveys showed no significant difference in the intake of energy and nutrients. Conclusion Brazilian green propolis can lower the levels of serum glucose and IgA, and may affect the level of serum IgG.

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Brazilian green propolis / blood glucose / serum lipids / antibody / cytokines / the elderly

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GAO Wei-na, WEI Jing-yu, WU Jian-quan, PU Ling-ling, GUO Chang-jiang. EFFECTS OF BRAZILIAN GREEN PROPOLIS ON SERUM BIOCHEMICAL AND IMMUNO-INFLAMMATORY PARAMETERS IN THE ELDERLY[J]. Acta Nutrimenta Sinica. 2024, 46(5): 457-461

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