营养补充与皮肤健康专家共识

Acta Nutrimenta Sinica ›› 2025, Vol. 47 ›› Issue (3) : 209-215.

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Acta Nutrimenta Sinica ›› 2025, Vol. 47 ›› Issue (3) : 209-215.
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[1] World Health Organization.WHO handbook for guideline development[M]. 2nd edition. Geneva:World Health Organization, 2014.
[2] 国家市场监督管理总局. 市场监管总局关于公布《保健食品新功能及产品技术评价实施细则(试行)》的公告[R/OL]. (2023-08-13)[2025-06-12].https://www.gov.cn/zhengce/zhengceku/202308/content_6900636.htm.
[3] Maia Campos P, Franco RSB, Kakuda L, et al. Oral supplementation with hydrolyzed fish cartilage improves the morphological and structural characteristics of the skin: a double-blind, placebo-controlled clinical study[J]. Molecules, 2021, 26: 4880.
[4] Himeno A, Tsujikami M, Koizumi S, et al. Effect of reducing pigmentation by collagen peptide intake: a randomized, double-blind, placebo-controlled study[J]. Dermatol Ther (Heidelb), 2022, 12: 1577–1587.
[5] Inoue N, Sugihara F, Wang X.Ingestion of bioactive collagen hydrolysates enhance facial skin moisture and elasticity and reduce facial ageing signs in a randomised double-blind placebo-controlled clinical study[J]. J Sci Food Agric, 2016, 96: 4077–4081.
[6] Proksch E, Schunck M, Zague V, et al. Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis[J]. Skin Pharmacol Physiol, 2014, 27: 113–119.
[7] Seong SH, Lee Y I, Lee J, et al. Low-molecular-weight collagen peptides supplement promotes a healthy skin: a randomized, double-blinded, placebo-controlled study[J]. J Cosmet Dermatol, 2024, 23: 554–562.
[8] Lee JS, Yoon YC, Kim JM, et al. Liquid collagen from freshwater fish skin ameliorates hydration, roughness and elasticity in photo-aged skin: a randomized, controlled, clinical study[J]. Nutr Res Pract, 2024, 1: 357–371.
[9] Maia Campos P, Melo MO, Siqueira César FC.Topical application and oral supplementation of peptides in the improvement of skin viscoelasticity and density[J]. J Cosmet Dermatol, 2019, 18: 1693–1699.
[10] Asserin J, Lati E, Shioya T, et al. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials[J]. J Cosmet Dermatol, 2015, 14: 291–301.
[11] Kim DU, Chung HC, Choi J, et al. Oral intake of low-molecular-weight collagen peptide improves hydration, elasticity, and wrinkling in human skin: a randomized, double-blind, placebo-controlled study[J]. Nutrients, 2018, 1:826.
[12] Gao YR, Wang RP, Zhang L, et al. Oral administration of hyaluronic acid to improve skin conditions via a randomized double-blind clinical test[J]. Skin Res Technol, 2023, 29: e13531.
[13] Michelotti A, Cestone E, De Ponti I, et al. Oral intake of a new full-spectrum hyaluronan improves skin profilometry and ageing: a randomized, double-blind, placebo-controlled clinical trial[J]. Eur J Dermatol, 2021, 31: 798–805.
[14] Oe M, Sakai S, Yoshida H, et al. Oral hyaluronan relieves wrinkles: a double-blinded, placebo-controlled study over a 12-week period[J]. Clin Cosmet Investig Dermatol, 2017, 10: 267–273.
[15] Hsu TF, Su ZR, Hsieh YH, et al. Oral hyaluronan relieves wrinkles and improves dry skin: a 12-week double-blinded, placebo-controlled study[J]. Nutrients, 2021, 13: 2220.
[16] Ito N, Seki S, Ueda F.The protective role of astaxanthin for UV-induced skin deterioration in healthy people-a randomized, double-blind, placebo-controlled trial[J]. Nutrients, 2018, 10: 817.
[17] Tominaga K, Hongo N, Karato M, et al. Cosmetic benefits of astaxanthin on humans subjects[J]. Acta Biochim Pol, 2012, 59: 43-47.
[18] Phetcharat L, Wongsuphasawat K, Winther K.The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity[J]. Clin Interv Aging, 2015, 10: 1849–1856.
[19] Tominaga K, Hongo N, Fujishita M, et al. Protective effects of astaxanthin on skin deterioration[J]. J Clin Biochem Nutr, 2017, 61: 33–39.
[20] Kang S, Park J, Cheng Z, et al. Novel approach to skin anti-aging: boosting pharmacological effects of exogenous nicotinamide adenine dinucleotide (NAD(+)) by synergistic inhibition of CD38 expression[J]. Cells, 2024, 13: 1799.
[21] Yoshizumi M, Nakamura T, Kato M, et al. Release of cytokines/chemokines and cell death in UVB-irradiated human keratinocytes, HaCaT[J]. Cell Biol Int, 2008, 32: 1405–1411.
[22] Allen NC, Martin AJ, Snaidr VA, et al. Nicotinamide for skin-cancer chemoprevention in transplant recipients[J]. N Engl J Med, 2023, 388: 804–812.
[23] Chen AC, Martin AJ, Choy B, et al. A phase 3 randomized trial of nicotinamide for skin-cancer chemoprevention[J]. N Engl J Med, 2015, 373: 1618–1626.
[24] Marini A, Grether-Beck S, Jaenicke T, et al. Pycnogenol® effects on skin elasticity and hydration coincide with increased gene expressions of collagen type I and hyaluronic acid synthase in women[J]. Skin Pharmacol Physiol, 2012, 25: 86–92.
[25] Zhao H, Wu J, Wang N, et al. Oral pycnogenol® intake benefits the skin in urban chinese outdoor workers: a randomized, placebo-controlled, double-blind, and crossover intervention study[J]. Skin Pharmacol Physiol, 2021, 34: 135-145.
[26] Saliou C, Rimbach G, Moini H, et al. Solar ultraviolet-induced erythema in human skin and nuclear factor-kappa-B-dependent gene expression in keratinocytes are modulated by a French maritime pine bark extract[J]. Free Radic Biol Med, 2001, 30: 154–160.
[27] Lauer AC, Groth N, Haag SF, et al. Dose-dependent vitamin C uptake and radical scavenging activity in human skin measured with in vivo electron paramagnetic resonance spectroscopy[J]. Skin Pharmacol Physiol, 2013, 26: 147–154.
[28] McArdle F, Rhodes LE, Parslew R, et al. UVR-induced oxidative stress in human skin in vivo: effects of oral vitamin C supplementation[J]. Free Radic Biol Med, 2002, 33: 1355–1362.
[29] Fuchs J, Kern H.Modulation of UV-light-induced skin inflammation by D-alpha-tocopherol and L-ascorbic acid: a clinical study using solar simulated radiation[J]. Free Radic Biol Med, 1998, 25: 1006–1012.
[30] Nachbar F, Korting H C.The role of vitamin E in normal and damaged skin[J]. J Mol Med (Berl), 1995, 73: 7–17.
[31] Mireles-Rocha H, Galindo I, Huerta M, et al. UVB photoprotection with antioxidants: effects of oral therapy with d-alpha-tocopherol and ascorbic acid on the minimal erythema dose[J]. Acta Derm Venereol, 2002, 82: 21–24.
[32] Cheah IK, Halliwell B.Ergothioneine, recent developments[J]. Redox Biol, 2021, 42: 101868.
[33] Hseu YC, Lo HW, Korivi M, et al. Dermato-protective properties of ergothioneine through induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated human keratinocytes[J]. Free Radic Biol Med, 2015, 86: 102–117.
[34] Hanayama M, Mori K, Ishimoto T, et al. Effects of an ergothioneine-rich Pleurotus sp. on skin moisturizing functions and facial conditions: a randomized, double-blind, placebo-controlled trial[J]. Front Med (Lausanne), 2024, 11: 1396783.
[35] Liu X, Yuen M, Yuen T, et al. Anti-skin aging effect of sea buckthorn proanthocyanidins in D-galactose-induced aging mice[J]. Food Sci Nutr, 2024, 12: 1082–1094.
[36] Yamakoshi J, Sano A, Tokutake S, et al. Oral intake of proanthocyanidin-rich extract from grape seeds improves chloasma[J]. Phytother Res, 2004, 18: 895–899.
[37] Tsuchiya T, Fukui Y, Izumi R, et al. Effects of oligomeric proanthocyanidins (OPCs) of red wine to improve skin whitening and moisturizing in healthy women - a placebo-controlled randomized double-blind parallel group comparative study[J]. Eur Rev Med Pharmacol Sci, 2020, 24: 1571–1584.
[38] de Oliveira JR, Camargo SEA, de Oliveira LD. Rosmarinus officinalis L. (rosemary) as therapeutic and prophylactic agent[J]. J Biomed Sci, 2019, 26: 5.
[39] Yu L, McGarry S, Cruickshank D, et al. Rapid increase in immune surveillance and expression of NKT and γδT cell activation markers after consuming a nutraceutical supplement containing Aloe vera gel, extracts of Poria cocos and rosemary. A randomized placebo-controlled cross-over trial[J]. PLoS One, 2023, 18: e0291254.
[40] Groten K, Marini A, Grether-Beck S, et al. Tomato phytonutrients balance uv response: results from a double-blind, randomized, placebo-controlled study[J]. Skin Pharmacol Physiol, 2019, 32: 101–108.
[41] H C. Nathral Health Product Hydrolyzed Collagen[R/OL]. (2024-03-08)[2025-05-18].https://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq?atid=hydrolized.collagen&lang=eng, Health Canada, 2024.
[42] Becker LC, Bergfeld W F, Belsito DV, et al. Final report of the safety assessment of hyaluronic acid, potassium hyaluronate, and sodium hyaluronate[J]. Int J Toxicol, 2009, 28(4 Suppl): 5–67.
[43] Brendler T, Williamson EM.Astaxanthin: how much is too much? A safety review[J]. Phytother Res, 2019, 33: 3090–3111.
[44] 欧盟食品安全局就两种虾青素产品作为新型食品配料的安全性发布科学意见[J]. 食品与生物技术学报, 2014, 33: 1002.
[45] EFSA. Scientific opinion on dietary reference values for niacin[J]. EFSA J, 2014, 12: 3759.
[46] Snaidr VA, Damian DL, Halliday G M.Nicotinamide for photoprotection and skin cancer chemoprevention: a review of efficacy and safety[J]. Exp Dermatol, 2019, 28(Suppl 1): 15–22.
[47] 陈世伟刘翠娥, 张杰,等. 碧箩芷的毒理学研究[J]. 河南预防医学杂志, 2003,14: 19–25.
[48] Li YY, Feng J, Zhang XL, et al. Pine bark extracts: nutraceutical, pharmacological, and toxicological evaluation[J]. J Pharmacol Exp Ther, 2015, 353: 9–16.
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