PROGRESS ON THE PATHOGENESIS OF PLATEAU HYPERURICEMIA AND NUTRITIONAL INTERVENTION

LV Fei, BAI Chen, ZHANG Yu-xian, SUN Tie-qiang, HOU Li-xue, YU Li-xia

Acta Nutrimenta Sinica ›› 2026, Vol. 48 ›› Issue (2) : 193-199.

Acta Nutrimenta Sinica ›› 2026, Vol. 48 ›› Issue (2) : 193-199.

PROGRESS ON THE PATHOGENESIS OF PLATEAU HYPERURICEMIA AND NUTRITIONAL INTERVENTION

  • LV Fei1, BAI Chen4, ZHANG Yu-xian2, SUN Tie-qiang2, HOU Li-xue3, YU Li-xia2
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Abstract

The plateau environments are extremely prone to inducing metabolic disorders. Hyperuricemia, a common metabolic disorder syndrome in plateaus, is primarily associated with increased endogenous uric acid synthesis, impaired uric acid excretion, inflammation and oxidative stress, and intestinal dysfunction. Due to the numerous contra-indications and side effects of current therapeutic drugs, there is an urgent need to develop safe and effective nutritional interventions. Numerous studies have indicated that the supplementation with some nutrients, natural active ingredients and plant extracts holds potential advantages in the intervention of hyperuricemia. This review provides an overview on the pathogenesis of plateau-associated hyperuricemia and its potential nutritional intervention strategies, so as to provide references for the development of effective nutritional intervention against hyperuricemia in plateaus.

Key words

plateaus / hyperuricemia / nutrients / natural active ingredients / plant extracts

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LV Fei, BAI Chen, ZHANG Yu-xian, SUN Tie-qiang, HOU Li-xue, YU Li-xia. PROGRESS ON THE PATHOGENESIS OF PLATEAU HYPERURICEMIA AND NUTRITIONAL INTERVENTION[J]. Acta Nutrimenta Sinica. 2026, 48(2): 193-199

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