The experimental evidence of waveform information in arterial blood gas by beat-by-beat sampling method in human body—the differences of waveform information between arterial and venous blood samples

doi:10.12047/j.cjap.0077.2021.102

CJAP ›› 2021, Vol. 37 ›› Issue (1): 34-39.doi: 10.12047/j.cjap.0077.2021.102

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The experimental evidence of waveform information in arterial blood gas by beat-by-beat sampling method in human body—the differences of waveform information between arterial and venous blood samples

CUI Yan¹, SUN Xing-guo, CI Zheng^1,2, GE Wan-gang¹, LI Hao¹, WANG Gui-zhi^1,2, ZHU Jia-bao^1,3, LI Yin-jun^1,4, DENG Wei^1,5, MA Ming-xin^1,6, CHEN Rong^1,6, HUANG Yan^1,6, ZOU Yu-xin^1,7, TAN Xiao-yue¹, LIU Fang¹

1. Department of Cardiology,Fuwai Hospital,Chinese Academy of Medical Sciences/National Center for Cardiovascular Diseases/ State Key Laboratory of Cardiovascular Diseases/Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing 100037;
2. Weifang Medical University, Weifang 261053;
3. The Second Hospital of Hebei Medical University,Shijiazhuang 050005;
4. Kangle Hospital of Chengguan District, Lanzhou 730030;
5. The Affiliated Rehabilitation Hospital of Chongqing Medical University, Chongqing 400050;
6. Dalian Children's Hospital,Dalian 116000;
7. Liaocheng People's Hospital, Liaocheng 252000, China

Received:2020-08-12 Revised:2021-01-07 Published:2021-10-21

Abstract

Abstract: Objective: The arterial blood with the oscillatory information comes from the right heart system after gas exchanging in the lung. However, the evidence of the waveform of venous ABG is lack. The objectives of this article are to compare the different information between arterial and venous beat-by-beat blood sample at the same time. Methods: Six post-operative patients with normal heart function and negative Allen test, had been placed the arterial catheterization and central venous catheterization directly connected to pre-heparin plasticpipes for continuous collecting arterial and venous blood. We twisted the 2 pipes into helix formation. After drawing arterial and venous blood with syringes in one heart beat with one helix at the same time, totally 15 heart beats, clipping the pipes with forceps, we put the helix pipe into icedwater at once and analyses PaO₂, PaCO₂, pH and SaO₂ as soon as possible. We selected two breathscycles of waveform from each patient for data calculations of magnitudes and time interval. Results: The heart beat numbers for drawing blood into pipe were 15~16, and all covered more than 2 breathing cycles. There were significant changes of arterial PaO₂(i.e. the highest high values compare to the next lowestvalues, P<0.05), but no significant changes in venous blood(P>0.05). The magnitudes of changing PaO₂ in arterial and venous blood sample were (9.96±5.18)mmHg and (1.63±0.41)mmHg with significant variance(P=0.010), and they were (8.09±2.43)% and (3.91±1.22)%from their mean with significant variance(P=0.009) respectively. Conclusion: With continuous beat-by-beat arterial and venous blood sampling and ABG analyzing method at the same time, we obtain a clear evidence of periodic parameters ABG waveform, which following breathing cycle, but no clear ABG waveform of the periodic parameters in the venous blood samples, which implies the oscillatory information of the arterial blood with comes from the gas exchanging in the lung.

Key words: arterial blood gas, venous blood gas, breathing control, beat-by-beatsampling, waveform information

CLC Number:

R332.3

CUI Yan, SUN Xing-guo, CI Zheng, GE Wan-gang, LI Hao, WANG Gui-zhi, ZHU Jia-bao, LI Yin-jun, DENG Wei, MA Ming-xin, CHEN Rong, HUANG Yan, ZOU Yu-xin, TAN Xiao-yue, LIU Fang. The experimental evidence of waveform information in arterial blood gas by beat-by-beat sampling method in human body—the differences of waveform information between arterial and venous blood samples[J]. CJAP, 2021, 37(1): 34-39.

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The experimental evidence of waveform information in arterial blood gas by beat-by-beat sampling method in human body—the differences of waveform information between arterial and venous blood samples

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