Abstract：Objective To provide evidences for the formulation of influenza vaccination strategies in troops by evaluating the effect of influenza vaccination in recruits in an army.Methods We vaccinated 292 recruits with influenza vaccine as the experimental group and in the same theater selected 1472 recruits of similar conditions as a control group in October 2014. The investigation was performed during recruits' military training which was started from 70 days after vaccination.Results There was a significant difference in influenza-like febrile illness incidence between experimental group and control group. The protection rate of influenza vaccine for influenza-like febrile illness was 89.1%. The benefit-cost ratio (BCR) of influenza vaccination 70 days after inoculation during recruits' training was 5.44:1.Conclusion Recruits should be vaccinated by influenza vaccine as soon as they arrived in troops, so as to reduce cases of flu-like fever, as well as losses caused by the influenza.
高东旗, 杨会锁, 宋文静, 甘露, 李宏, 邓兵. 某部新兵流感疫苗接种效果及效益分析[J]. 解放军预防医学杂志, 2016, 34(3): 342-344.
GAO Dongqi, YANG Huisuo, SONG Wenjing, GAN Lu, LI Hong, DENG Bing. Effect and Cost-Benefit Study of Influenza Vaccination in Recruits in an Army. Journal of Preventive Medicine of Chinese People's Liberation Army, 2016, 34(3): 342-344.
〔1〕 杨绍基.传染病学〔M〕.北京:人民卫生出版社,2006:51-54. 〔2〕 VU T,FARISH S,JENKINS M,et al.A meta-analysis of effectiveness of influenza vaccine in persons aged 65 years and over living in the community〔J〕.Vaccine,2002,20: 1831. 〔3〕 REED C, KIM I K, SINGLETON J A,et al.Estimated influenza illnesses and hospitalizations averted by vaccination--United States, 2013-14 influenza season〔J〕.MMWR Morb Mortal Wkly Rep,2014,63(49):1151. 〔4〕 中华人民共和国卫生部.WS 285-2008.流行性感冒诊断标准〔S〕.北京:人民卫生出版社,2008. 〔5〕 国家食品药品监督管理局(CFDA).疫苗临床试验技术指导原则〔S〕.2004. 〔6〕 国家食品药品监督管理局(CFDA).预防用疫苗临床试验不良反应分级标准指导原则〔S〕.2005. 〔7〕 刘民,刘改芬,王岩,等.北京市人群流感疫苗接种的效果效益评价研究〔J〕.中国全科医学,2005,8(15):1238. 〔8〕 FOPPA I M, CHENG P Y, REYNOLDS S B,et al.Deaths averted by influenza vaccination in the U.S. during the seasons 2005/06 through 2013/14〔J〕.Vaccine,2015,33(26):3003. 〔9〕 郭万申,徐瑾,吴俊燏,等.季节性流感裂解疫苗安尔来福的安全性、免疫原性及与H7N9禽流感病毒的交叉免疫研究〔J〕.中华流行病学杂志.2014,35(8):949. 〔10〕 LEE B Y,BARTSCH S M,BROWN S T,et al.Quantifying the economic value and quality of life impact of earlier influenza vaccination〔J〕.Med Care,2015,53(3):218. 〔11〕 宋倩倩,张艳平.某市65岁以上参保人员流感疫苗接种的效果观察〔J〕.中国医药指南,2014,12(34):84. 〔12〕 边申溦,马爱霞.我国流感疫苗接种策略经济学评价综述〔J〕.现代商贸工业,2015,36(2):54. 〔13〕 边国林,许国章,朱利利.季节性流感疫苗接种效果观察〔J〕.浙江预防医学,2010,22(1):12. 〔14〕 张之伦,王旭,朱向军,等.成年人连续三批次流感裂解疫苗接种的安全性、免疫原性观察〔J〕.中华流行病学杂志,2009,30(6):583. 〔15〕 YAMIN D, BALICER R D,GALVANI A P.Cost-effectiveness of influenza vaccination in prior pneumonia patients in Israel〔J〕.Vaccine,2014,32(33):4198. 〔16〕 CLEMENTS K M, MEIER G, MCGARRY L J,et al.Cost-effectiveness analysis of universal influenza vaccination with quadrivalent inactivated vaccine in the United States〔J〕.Hum Vaccin Immunother,2014,10(5):1171. 〔17〕 NEWALL A T, DEHOLLAIN J P.The cost-effectiveness of influenza vaccination in elderly Australians: an exploratory analysis of the vaccine efficacy required〔J〕.Vaccine, 2014,32(12):1323. 〔18〕 ZHOU F, SHEFER A, WENGER J,et al. Economic evaluation of the routine childhood immunization program in the United States,2009〔J〕.Pediatrics,2014,133(4):577. 〔19〕 赵艳伟,冯子健.国产与进口流行性感冒病毒裂解疫苗安全性和免疫原性的Meta分析〔J〕.中国疫苗和免疫,2009,15(1):19. 〔20〕 PALACHE A, ORIOL-MATHIEU V, ABELIN A,et al.Seasonal influenza vaccine dose distribution in 157 countries (2004-2011)〔J〕.Vaccine,2014,32(48):6369.
2016, Vol. 34 
