Home  About Journal Instructions for Authors Editorial Board Subscribe Advertisement Messages Board Contact Us 中文

CJAP ›› 2016, Vol. 32 ›› Issue (6): 494-498.doi: 10.13459/j.cnki.cjap.2016.06.003

Previous Articles     Next Articles

Identification of susceptibility to acute mountain sickness by detecting vascular tone using a photoplethysmographic sensor

Xiao-min LUO1,2, Lei WANG1, Lei YANG1   

  1. 1. Tibet Branch, Beijing Genomics Institute, Lhasa 850032, China;
    2. Healthcare Dept., Beijing Genomics Institute, Shenzhen 518083, China
  • Received:2016-07-23 Revised:2016-10-24 Online:2016-11-28 Published:2018-06-19

Abstract: Objective: Vascular tone had shown the potential susceptibility to acute mountain sickness (AMS), however the detailed tendency has not been studied. Methods: Vascular tone, SpO2 and Rate pressure product (RPP) were studied in seventeen healthy subjects before and after rapid ascent from sea level to 3658 m. Human acute mountain sickness was evaluated by the Lake Louise Score (LLS). Results: Nine of the seventeen participants were diagnosed with AMS. On initial exposure, there was a significant decrease in vascular tone between subjects with and without AMS. Significance was also found in the decrease of SpO2 before and after rapid ascent but the differences between subjects with and without AMS did not reach significance during the initial phase. Conclusions:Vascular tone on initial exposure in response to rapid ascent is a possible sign of susceptibility to AMS. Conclusion: measurement of vascular tone using a wearable sensor throughout the acute phase response will provide numerical values of pathophysiology throughout the development of AMS.

Key words: vascular tone, reflection index, acute mountain sickness, susceptibility, photoplethysmographic sensor

Contact Email:editor@cjap.ac.cn
Copyright © 2015 CJAP, All Rights Reserved.
Powered by Beijing Magtech Co. Ltd