Regulatory mechanisms of PAR-2 on CyclinD1 in the proliferation of esophageal cancer cells

doi:10.12047/j.cjap.5815.2019.123

Abstract

CLC Number:

R571

ZHANG Qi-liang, CAO Wen-li, DENG Quan-jun. Regulatory mechanisms of PAR-2 on CyclinD1 in the proliferation of esophageal cancer cells[J]. CJAP, 2019, 35(6): 559-562.

[1] 傅剑华, 谭子辉. 食管癌外科治疗的现状与未来展望[J]. 中国肿瘤临床, 2016, 43(12): 507-510.
[2] 唐安球, 周华富. 食管癌治疗现状及进展[J]. 医学综述, 2014, 20(1): 39-41.
[3] Grimsey N, Soto AG, Trejo J. Regulation of protease-activated receptor signaling by post-translational modifications[J]. IUBMB Life, 2011, 63(6): 403-411.
[4] Zebedee Z, Hara E. Id proteins in cell cycle control and cellularsenescence[J]. Oncogene, 2001, 20(58): 8317-8325.
[5] DeGregori J. The Rbnetwork[J]. J Cell Sci, 2004, 117(Pt 16): 3411-3413.
[6] 陈金梅, 谢立群, 邓全军, 等. PAR-2基因沉默对食管癌EC109细胞增殖及侵袭转移的影响[J]. 实用医学杂志, 2015, 31(1): 35-38.
[7] 陈金梅, 邓全军, 谢立群, 等. 蛋白酶激活受体-2基因靶向shRNA表达质粒的构建及转染食管癌细胞致沉默效应的研究[J]. 实用医学杂志, 2013, 29(3): 349-351.
[8] ChenJ, Xie L, Zheng Y, et al. Effects of silenced PAR-2 on cell proliferation, invasion and metastasis of esophageal cancer[J]. Oncology letters, 2017, 14(4): 4115-4121.
[9] Ossovskaya VS, Bunnett NW. Protease-activated receptors: contribution to physiology and disease[J]. Physiol Rev, 2004, 84(2): 579-621.
[10]Awasthi V, Mandal SK, Papanna V, et al. Modulation of tissue factor-factor VIIa signaling by lipid rafts and caveolae[J]. Arterioscler Thromb Vasc Biol, 2007, 27(6): 1447-1455.
[11]Kaufmann R, Mussbach F, Henklein P, et al. Proteinase-activated receptor 2-mediated calcium signaling in hepatocellular carcinoma cells[J]. J Cancer Res ClinOncol, 2011, 137(6): 965-973.
[12]Kaufmann R, Oettel C, Horn A, et al. Met receptor tyrosine kinase transactivation is involved in proteinase-activated receptor-2-mediated hepatocellular carcinoma cell invasion[J]. Carcinogenesis, 2009, 30(9): 1487-1496.
[13]Xie L, Zheng Y, Li X, et al. Enhanced proliferation of human hepatoma cells by PAR-2 agonists via the ERK/AP-1 pathway[J]. Oncol Rep, 2012, 28(5): 1665-1672.
[14]Xie L, Duan Z, Liu C, et al. Protease-activated receptor 2 agonist increases cell proliferation and invasion of human pancreatic cancer cells[J]. Exp Ther Med, 2015, 9(1): 239-244.
[15]Ungefroren H, Witte D, Rauch BH, et al. Proteinase-activated receptor 2 may drive cancer progression by facilitating TGF-β signaling[J]. Int J Mol Sci, 2017, 18(11). pii: E2494.
[16]李秀娟, 李玉珍, 金春亭, 等. 姜黄素作用 PTEN /PI3K /AKT 通路诱导食管癌 EC109 细胞凋亡[J]. 中国应用生理学杂志, 2015, 31(2): 174-177.
[17]席义博, 张皓旻, 杨波, 等. 人肝细胞癌预后不良相关基因的生物信息学分析及其临床意义[J]. 中国应用生理学杂志, 2019, 35(1): 90-96.
[18]李秀娟, 罗强, 孙黎, 等. 姜黄素对食管癌 Ec109 细胞增殖和 PTEN /PI3K /Akt 信号通路的影响[J]. 中国应用生理学杂志, 2015, 31(5): 465-468.

Regulatory mechanisms of PAR-2 on CyclinD1 in the proliferation of esophageal cancer cells

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