Glycyrrhetinic acid inhibits proliferation of osteosarcoma cell line MG63 by inhibiting NF-κB signaling pathway

doi:10.12047/j.cjap.5966.2020.085

Abstract

CLC Number:

DONG Song, LIU Pei-min, DU Xiang-yang, LI Feng-yan, CAO Ying, LIN Da-yong, BAI Jian. Glycyrrhetinic acid inhibits proliferation of osteosarcoma cell line MG63 by inhibiting NF-κB signaling pathway[J]. CJAP, 2020, 36(5): 399-401.

References

[1] 易生辉, 秦刚, 黄肖华, 等. 骨肉瘤的治疗进展[J]. 医学综述, 2017, 23(8): 1529-1532.
[2] Pan JX. LncRNA H19 promotes atherosclerosis by regulating MAPK and NF-κB signaling pathway[J]. Eur Rev Med PharmacolSci, 2017, 21(2): 322-328.
[3] 常明向, 吴梅梅, 李瀚旻. 姜黄素与甘草次酸联用对肝癌HepG-2细胞增殖的抑制作用[J]. 药物评价研究, 2017, 40(1): 42-47.
[4] 李国远, 郭煜, 罗正亮, 等. 白藜芦醇抑制骨肉瘤细胞侵袭实验研究[J]. 国际骨科学杂志, 2019, 40(3): 49-55.
[5] 姚俊杰, 迟寅秀, 高福莲. 甘草次酸对人胃癌SGC7901细胞增殖的影响及机制[J]. 新乡医学院学报, 2016, 33(7): 577-580.
[6] 尹素改, 周凌, 吴耀松, 等. 甘草次酸对人食管癌Eca9706细胞生长的抑制作用及机制[J]. 中国实验方剂学杂志, 2015, 21(4): 112-114.
[7] 贾洪岩, 林芳, 王立敏, 等. 甘草次酸对人胃癌HGC-27的抑制增殖和诱导凋亡作用[J]. 黑龙江医药科学, 2016, 39(2): 88-90.
[8] Pirzadeh S, Fakhari S, Jalili A, et al. Glycyrrhetinic acid induces apoptosis in leukemic HL60 cells through upregulating of CD95/CD178 [J]. Int J Mol Cell Med, 2014, 3(4): 272-278.
[9] Sharma G, Kar S, Palit S, et al. 18 beta-glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF-7 cells [J]. J Cell Physiol, 2012, 227(5): 1923-1931.
[10]李凤岩, 陈亚光 , 林大勇, 等. 甘草次酸对甲状腺癌细胞 SW579 凋亡的影响及其机制[J]. 中国应用生理学杂志, 2019, 35(5): 464-467.
[11]张瑞奎, 汪超. 苦参碱对大鼠乳腺癌细胞荷瘤生长及其炎性因子与免疫功能的影响[J]. 中国应用生理学杂志, 2018, 34(4): 375-378.
[12]王玉峰, 王岩峰, 胡春吉, 等. NF-κB抑制剂PDTC对骨肉瘤细胞MG63凋亡及Livin和Caspase-9的影响[J]. 中国矫形外科杂志, 2011, 19(7): 589-591.

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