核桃仁预防阿尔茨海默病作用活性成分的筛选

孙小雅; 路敏; 邢世松; 张彦飞; 李绍建; 田粟

营养学报 ›› 2024, Vol. 46 ›› Issue (1) : 102-104.

简报

孙小雅^1,2,3, 路敏^4,5, 邢世松^4,5, 张彦飞^4,5, 李绍建³, 田粟^1,2

作者信息 +

In Vitro Screening for Active Constituents of Walnut Kernel in the Prevention of Alzheimer's Disease

SUN Xiao-ya^1,2,3, LU Min^4,5, XING Shi-song^4,5, ZHANG Yan-fei^4,5, LI Shao-jian³, TIAN Su^1,2

Author information +

文章历史 +

导出引用

孙小雅, 路敏, 邢世松, 张彦飞, 李绍建, 田粟. 核桃仁预防阿尔茨海默病作用活性成分的筛选[J]. 营养学报. 2024, 46(1): 102-104

SUN Xiao-ya, LU Min, XING Shi-song, ZHANG Yan-fei, LI Shao-jian, TIAN Su. In Vitro Screening for Active Constituents of Walnut Kernel in the Prevention of Alzheimer's Disease[J]. Acta Nutrimenta Sinica. 2024, 46(1): 102-104

参考文献

[1] Zhang B, Zhao J, Wang Z, et al. Identification of multi-target anti-AD chemical constituents from traditional Chinese medicine formulae by integrating virtual screening and in vitro validation[J]. Front Pharmacol, 2021, 12:709607.
[2] Hu YH, Yang J, Zhang Y, et al. Synthesis and biological evaluation of 3-(4-aminophenyl)-coumarin derivatives as potential anti-alzheimer's disease agents[J]. J Enzyme Inhib Med Chem, 2019, 34:1083–1092.
[3] Gong CX, Liu F, Iqbal K.Multifactorial hypothesis and multi-targets for alzheimer's disease[J]. J Alzheimers Dis, 2018, 64:S107–S117.
[4] Cahoon D, Shertukde SP, Avendano EE, et al. Walnut intake, cognitive outcomes and risk factors:a systematic review and meta-analysis[J]. Ann Med, 2021,53:971–997.
[5] Chauhan A, Chauhan V.Beneficial effects of walnuts on cognition and brain health[J]. Nutrients, 2020, 12: 550.
[6] Tung BT, Thu DK, Thu NTK, et al. Antioxidant and acetylcholinesterase inhibitory activities of ginger root (Zingiber officinale Roscoe) extract [J/OL].J Complement Integr Med,2017,14:/j/jcim.2017.14. issue-4/jcim-6-0116/jcim-2016-0116.xml.
[7] Rusu ME, Gheldiu AM, Mocan A, et al. Process opti- mization for improved phenolic compounds recovery from walnut (Juglans regia L.) septum:Phytochemical profile and biological activities[J]. Molecules, 2018, 23: 2814.
[8] Zhang B, Deng Z, Ramdath DD, et al. Phenolic profiles of 20 canadian lentil cultivars and their contribution to antioxidant activity and inhibitory effects on alpha-glucosidase and pancreatic lipase[J]. Food Chem, 2015, 172:862–872.
[9] Kwon SH, Wang Z, Hwang SH, et al. Comprehensive evaluation of the antioxidant capacity of perilla frutescens leaves extract and isolation of free radical scavengers using step-wise HSCCC guided by DPPH-HPLC[J]. Int J Food Prop, 2017, 20:S921–S934.
[10] Kumar BSA, Lakshman K, Jayaveera KN, et al. Antioxidant and antipyretic properties of methanolic extract of amaranthus spinosus leaves[J]. Asian Pac J Trop Med, 2010, 3:702–706.
[11] 王微. 香水莲花提取物改善阿尔兹海默症学习记忆能力的作用研究 [D]. 杭州:浙江大学, 2019.
[12] Temviriyanukul P, Sritalahareuthai V, Promyos N, et al. The effect of sacred lotus (Nelumbo nucifera) and its mixtures on phenolic profiles, antioxidant activities, and inhibitions of the key enzymes relevant to alzheimer's disease[J]. Molecules, 2020, 25:3713.
[13] Ado MA, Abas F, Leong SW, et al. Chemical constituents and biological activities of Callicarpa maingayi leaves[J]. S Afr J Bot,2016,104:98–104.
[14] Moneim A E.Oxidant/antioxidant imbalance and the risk of Alzheimer's disease[J]. Curr Alzheimer Res, 2015, 12:335–349.
[15] 李煦. 核桃仁抗氧化、降血压作用及提取工艺研究 [D]. 贵阳:贵州师范大学, 2015.
[16] Zhang Z, Liao L, Moore J, et al. Antioxidant phenolic compounds from walnut kernels (Juglans regia L.)[J]. Food Chem, 2009, 113:160–165.