目的 探讨营养包作为6~24月龄婴幼儿辅食补充剂,对婴幼儿唾液中分泌型免疫球蛋白A含量的影响。方法 选择营养包干预地区和其临近未干预地区的婴幼儿,进行早期儿童营养干预与非干预人群营养健康状况的长期队列观察。干预组婴幼儿在6~24月龄期间每日辅食中添加一袋营养包,对照组不服用营养包,此外同时为对照组和干预组提供科学健康喂养指导。在2018年至2020年连续3年的监测中,收集婴幼儿唾液并检测其唾液中免疫球蛋白A含量,并对婴幼儿唾液中免疫球蛋白A的含量变化情况进行比较和分析。结果 本研究婴幼儿唾液中的免疫球蛋白A含量随着月龄的增加呈增加的趋势,干预组和对照组婴幼儿在2018年基线阶段的免疫球蛋白A含量没有显著性差异。2019年和2020年干预组婴幼儿唾液中的免疫球蛋白A含量均高于地域邻近的对照组,差异有统计学意义（P<0.05）。结论 营养包干预能够提升婴幼儿唾液中免疫球蛋白A水平,增强婴幼儿免疫力。
Abstract
Objective To investigate the effect of Yingyang Bao (YYB) intervention on the levels of secretory immunoglobulin A (sIgA) in the saliva of infants and young children (IYC) aged 6-24 months. Methods IYC in the intervention area with YYB and the adjacent areas not intervened with YYB were selected to observe their nutrition and health status after nutrition intervention. IYC in the intervention group were given a daily bag of YYB during the period of 6-24 months, while those in the control group were not. In addition, scientific and healthy feeding guidance was provided for both the control group and the intervention group. During three consecutive years from 2018 to 2020, the saliva samples were collected and the content of sIgA was detected, and the changes of the content of sIgA in their saliva were compared and analyzed. Results In this study, the content of sIgA in saliva of IYC increased with months, and there was no significant difference in the content of sIgA between the intervention group and the control group at the baseline stage in 2018. In 2019 and 2020, the content of sIgA in saliva in the intervention group was higher than that in the neighboring control group, and the difference was statistically significant (P<0.05). Conclusion Yingyang Bao can improve the level of sIgA in saliva and enhance the immunity in infants and young children.
关键词
婴幼儿 /
营养包 /
唾液 /
免疫球蛋白A
Key words
infants and young children /
Yingyang Bao /
saliva /
immunoglobulin A
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基金
早期儿童营养包干预长期营养健康作用评估(No.131031107000200001)
