Relationship of characteristic duration and magnitude of the oscillatory breathing related with exercise functional capacity in patients with chronic heart failure

doi:10.12047/j.cjap.0076.2021.121

Abstract

Abstract: Objective: To find out the relationship between the duration and amplitude of oscillatory breathing (OB) and their exercise capacity in patients with chronic heart failure (CHF) we did this study. Methods: Two hundred and thirty-seven CHF patients performed a maximum incremental upright cycle ergometry cardiopulmonary exercise testing (CPET). Respiratory gas exchange was measured on a breath-by-breath basis throughout the test. OB was defined as 3 or more continuous cycle fluctuations of ventilation during CPET, and the amplitude of VE oscillations exceed 25% of concurrent mean value. The CHF patients with OB (OB+) were divided into 3 sub-groups according to their Peak VO₂. Group1 (mild OB+) Peak VO₂ of ≥16 ml/min/kg, group 2 (moderate OB+) Peak VO₂ is between 12~16 ml/min/kg, group 3 (severe OB+) Peak VO₂ ≤ 12 ml/(min·kg). Results: There were 78(32.6%) patients detected as OB+ in 237 CHF patients. Among OB+ patients, OB duration in s related negatively to Peak VO₂ in mL/min/kg (r=-0.82), Peak VO₂ in %pred (r=-0.65), VO₂ at AT (r=-0.78), and related positively to VE/VCO₂ at AT (r=0.61). Conclusion: OB duration is related negatively to exercise capacity of CHF patients.

Key words: chronic heart failure, cardiopulmonary exercise testing, oscillatory breathing, duration of oscillatory breathing, gas exchange

CLC Number:

R332.3

LYU Jing, LI Zhen-ci, SUN Xing-guo, William Stringer. Relationship of characteristic duration and magnitude of the oscillatory breathing related with exercise functional capacity in patients with chronic heart failure[J]. CJAP, 2021, 37(2): 169-176.

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