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CJAP ›› 2021, Vol. 37 ›› Issue (2): 202-207.doi: 10.12047/j.cjap.0097.2021.125

• ORIGINAL ARTICLES • Previous Articles     Next Articles

Effects of cardiac rehabilitation protocol centered with personalized - exercise training on further improvement of holistic function in patients with coronary heart disease after percutaneous coronary intervention

ZHANG Zhen-ying1, SUN Xing-guo1,2△, SUN Xiao-jing1, FENG Jing1, XI Jia-ning1, YU Hong1, TAI Wen-qi2, LIU Fang2, ZHANG Ye2, LIU Yan-ling1, WANG Li-zhong1   

  1. 1. Cardiac Rehabilitation Center,Beijing Rehabilitation Hospital of Capital Medical University, Beijing 100144;
    2. National Center for Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Disease Clinical Medicine Research, Beijing 100037, China
  • Received:2020-08-12 Revised:2021-03-15 Online:2021-03-28 Published:2021-10-20

Abstract: Objective: To investigate the effects of cardiac rehabilitation protocol centered with personalized - exercise training (ET) on further improvement of holistic function in patients with stable angina after percutaneous coronary intervention (PCI). Methods: 20 patients who were diagnosed with stable angina in Beijing Rehabilitation Hospital from June 2016 to December 2019, were randomly divided into control group (n=10) and ET group (n=10). All patients were received PCI selectively. After PCI, patients in Control group were treated with conventional cardiac rehabilitation without ET; patients in ET group were treated with ET-based cardiac rehabilitation for 12 weeks. Cardiopulmonary exercise testing (CPET) parameters, echocardiogram and 6-minute walking distance (6MWD) of 2 groups of patients were recorded respectively before PCI, 2 weeks after PCI and 12 weeks after ET. Results: All patients in 2 groups finished symptom limited maximum CPET, and patients in ET group finished 12 weeks - ET safely without complications. Before PCI and 2 weeks after PCI, there were no differences in parameters including anaerobic threshold (AT), peak oxygen uptake, peak oxygen pulse, left ventricular ejection fraction (LVEF) and 6MWD between control group and ET group(P>0.05); after 12-week treatment, AT(ml/min,ml/(min·kg)), peak oxygen uptake(ml/(min·kg)), peak oxygen pulse(ml/beat) and 6MWD of patients in ET group were higher significantly than those of patients in control group (P<0.05). In ET group, the variables including AT (ml/min、ml/(min·kg)、%pred), peak oxygen uptake(ml/min,ml/(min·kg),%pred), peak oxygen pulse (ml/beat) and 6MWD of patients after 12-week ET were significantly higher than those of patients before PCI treatment (P<0.05); notably, AT (ml/(min·kg)) and peak oxygen uptake (ml/(min·kg)) of patients in ET group were significantly higher after 12-week ET program compared with those of patients 2 weeks after PCI ( P<0.05). In Control group, AT(ml/min)and peak oxygen pulse(ml/beat)of patients after 12-week treatment were higher than those of patients before PCI ( P<0.05), but there were no difference between 2 weeks after PCI and 12-week treatment ( P>0.05). Conclusion: Personalized - exercise training after PCI could further improve the cardiac function and exercise endurance, ET - based cardiac rehabilitation is an important part of secondary prevention for patients after PCI, which needs to be widely promoted.

Key words: coronary heart disease, percutaneous coronary intervention, exercise training, cardiac rehabilitation, cardiopulmonary exercise testing

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