36 h完全睡眠剥夺对客体工作记忆相关电位的影响*

doi:10.12047/j.cjap.6030.2020.124

中国应用生理学杂志 ›› 2020, Vol. 36 ›› Issue (6): 590-594.doi: 10.12047/j.cjap.6030.2020.124

36 h完全睡眠剥夺对客体工作记忆相关电位的影响^*

彭子伊¹, 陈学伟², 张颖³, 杨业兵³, 张立伟⁴, 邵永聪^1△

1.北京体育大学心理学院, 北京 100084;
2.军事医学研究院环境医学与作业医学研究所军事作业医学研究室, 天津 300050;
3.中国人民解放军总医院, 北京 100853;
4.中国科学院心理研究所, 北京 100101

收稿日期:2020-03-06 修回日期:2020-11-19 出版日期:2020-11-28 发布日期:2021-03-15
通讯作者: ^△E-mail: budeshao@aliyun.com
基金资助:
^*国家科技冬奥重点研发计划项目(2019YFF0301600)

Effect of 36h total sleep deprivation on the object working memory: an ERP study

PENG Zi-yi¹, CHEN Xue-wei², ZHANG Ying³, YANG Ye-bing³, ZHANG Li-wei⁴, SHAO Yong-cong^1△

1. School of Psychology, Beijing Sport University, Beijing 100084;
2. Department of Operational Medicine, Tianjin Institute of Environmental and Operational Medicine, Tianjin 300050;
3. The General Hospital of the People's Liberation Army, Beijing 100853;
4. Institute of Psychology of the Chinese Academy of Sciences, Beijing 100101, China

Received:2020-03-06 Revised:2020-11-19 Online:2020-11-28 Published:2021-03-15

摘要/Abstract

摘要： 目的:采用事件相关电位(ERP)技术探讨36 h完全睡眠剥夺对客体工作记忆的影响。方法:本研究采用自身前后对照设计,16名睡眠质量良好的健康大学生(平均年龄为23岁,年龄范围21～28岁)分别在清醒状态下及36 h完全睡眠剥夺后接受2-back客体工作记忆任务,同时采集脑电数据。选用重复测量方差分析的方法比较睡眠剥夺前后与客体工作记忆有关的P2、N2、P3成分的波幅和潜伏期的差异。结果:在36 h完全睡眠剥夺后,与客体工作记忆加工相关的N2波的潜伏期显著延长(P＜0.05),波幅减少但未见统计学差异(P＞0.05); P2波潜伏期显著延长(P＜0.05),波幅未见明显变化(P＞0.05)。P3波波幅、潜伏期未见统计学差异(P＞0.05)。结论:36 h的完全睡眠剥夺影响了客体工作记忆相关电位,损害了个体的客体工作记忆加工能力。

关键词: 睡眠剥夺, 客体工作记忆, 事件相关电位

Abstract: Objective: To investigate the effects of 36 h total sleep deprivation (TSD) on object working memory by event related potential(ERP). Methods: We used a pre-post-design, sixteen healthy college students (age range: 21-28 years, mean age: 23 years) received object working memory tasks while awake and after 36 hours of TSD and simultaneously recording electroencephalograph (EEG) data while completing 2-back object working memory tasks. ERP data were statistically analyzed using repeated measurements analysis of variance to observe the changes in the working memory-related P2, N2 and P3 components. Results: After 36 h TSD, the latency of N2 waves related to object working memory significantly was prolonged (P＜0.05), and the amplitude was decreased, but difference did not reach statistical significance (P＞0.05). The latency of P2 was significantly prolonged after TSD (P＜0.05). There was no significant difference in the change of latency and amplitude of P3 waves (P＞0.05). Conclusion: 36 h of total sleep deprivation affected working memory-related components and impaired object working memory capacity.

Key words: sleep deprivation, object working memory, ERP

中图分类号:

Q424

彭子伊, 陈学伟, 张颖, 杨业兵, 张立伟, 邵永聪. 36 h完全睡眠剥夺对客体工作记忆相关电位的影响^*[J]. 中国应用生理学杂志, 2020, 36(6): 590-594.

PENG Zi-yi, CHEN Xue-wei, ZHANG Ying, YANG Ye-bing, ZHANG Li-wei, SHAO Yong-cong. Effect of 36h total sleep deprivation on the object working memory: an ERP study[J]. CJAP, 2020, 36(6): 590-594.

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36 h完全睡眠剥夺对客体工作记忆相关电位的影响^*

Effect of 36h total sleep deprivation on the object working memory: an ERP study

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