Evidence of waveform information in arterial blood gas by beat-by-beat sampling method in patients with heart failure

doi:10.12047/j.cjap.0111.2015.006

Abstract

Abstract: Objective: We investigate the magnitudes of waveform changes of arterial blood gas (ABG) in patients with heart failure. Methods: Five patients with heart failure were selected, continuous collecting radial artery blood and measured PaO₂, PaCO₂, pHa and SaO₂. We selected two typical breaths cycles of waveform changes of ABG from each patient for data analysis. Comparison of the adjacent highest and lowest values to verify the presence of a periodic waveform changes of ABG, and in addition, we used t test to analysis the range of waveform changes of ABG in patients with heart failure and patients with normal cardiac function and compared whether the difference between them. Results: The 5 patients (2 surgical and 3 ICU) with heart failure, were 4 male and 1 female, (69±7)year, (169±10)cm, (75±19)kg, LVEF=(38±3)%. The heart beat numbers for full blood into the blood sampling pipe were 17±2, and all covered more than 2 breath cycles. There were significant changes of PaO₂, PaCO₂, [H⁺]a and SaO₂(P<0.05). The magnitudes of changing PaO₂, PaCO₂, [H⁺]a and SaO₂ were (7.94±2.02)mmHg, (1.18±0.56)mmHg, (0.54±0.17)nmol/L and (0.21±0.07)%, and they were (6.1±1.5)%, (3.2±1.5)%, (1.5±0.5)% and (0.2±0.1)% from their mean respectively. Even these magnitudes fo all ABG parameters were trendily lower than those of patients with normal cardiac function, but only PaO₂ and [H⁺]a were significant (P<0.05). Conclusion: Using this simple continuous beat-by-beat arterial blood sampling method, we obtained a clear evidence of periodic waveform of ABG parameters following by breath cycle in patients with heart failure, but the magnitude trendily be decreased.

Key words: heart failure, arterial blood gas, respiratory regulation, beat-by-beat arterial blood sampling, waveform signal

CLC Number:

R332.3

YAO You-xiu, SUN Xing-guo, LI Jun, TAN Xiao-yue, ZHANG Hong-liang, WANG Gu-yan, GE Wan-gang, LIU Fang, LI Hao, CI Zheng, HU Sheng-shou. Evidence of waveform information in arterial blood gas by beat-by-beat sampling method in patients with heart failure[J]. CJAP, 2015, 31(4): 322-326.

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