橘皮素对高强度运动诱发的人体皮质醇应激反应的影响*

doi:10.12047/j.cjap.6166.2021.055

中国应用生理学杂志 ›› 2021, Vol. 37 ›› Issue (5): 523-528.doi: 10.12047/j.cjap.6166.2021.055

橘皮素对高强度运动诱发的人体皮质醇应激反应的影响^*

刘猛¹, 莫仕围², 周志钦³, 高炳宏^1△

1.上海体育学院体育教育训练学院, 上海 200438;
2.深圳大学体育部, 深圳 518060;
3.西南大学园艺园林学院, 重庆 400700

收稿日期:2020-09-23 修回日期:2021-01-14 出版日期:2021-09-28 发布日期:2021-11-24
通讯作者: ^△Tel: 13817671181; E-mail: gaobinghong@126.com
基金资助:
^*国家重点研发计划“科技冬奥”重点专项——冬季项目运动疲劳消除关键技术研究与应用(2019YFF0301603); 国家体育总局体质评价与运动机能监控重点实验室

Effects of Tangeretin on cortisol stress response induced by high-intensity resistance exercise

LIU Meng¹, MO Shi-wei ², ZHOU Zhi-qin ³, GAO Bing-hong ^1△

1. College of Physical Education and Training, Shanghai University of Sport, Shanghai 200438;
2. Department of Physical Education, Shenzhen University, Shenzhen 518060;
3. College of Horticulture and Landscape Architecture, Southwest University, Chongqing 400700, China

Received:2020-09-23 Revised:2021-01-14 Online:2021-09-28 Published:2021-11-24

摘要/Abstract

摘要： 目的: 探讨4周橘皮素补充对高强度抗阻运动诱发的皮质醇应激反应的影响。方法: 将24名短跑运动员进行配对,随机分为试验组和对照组。试验组每天补充橘皮素补剂(含橘皮素200 mg),对照组每天补充安慰剂,为期4周。两组运动员均在干预前一日和干预后次日进行抗阻运动激发试验(推举、深蹲、卧推和硬拉,每个动作×4组×10RM)。采集受试者在运动激发试验前即刻(PRE)、试验后即刻(P0)以及第10(P10)、20(P20)和30(P30)分钟时的血液样本,测量血清皮质醇、促肾上腺皮质激素(ACTH)、超氧化物歧化酶(SOD)、白细胞计数(WBC)和血糖,以及PRE和P0时的血乳酸值。结果: 与干预前同期比较,补充橘皮素4周后,试验组在激发试验前PRE的血清皮质醇水平(P=0.017)、激发试验后P10的血清皮质醇水平(P=0.010)、激发试验后P20和激发试验后P30的血清皮质醇水平均显著降低(P＜0.05或 P＜0.01),试验组在激发试验前PRE的WBC、激发试验后P10的ACTH(P=0.037)和激发试验后P30的WBC、ACTH均显著降低(P＜0.05);与对照组比较,试验组在激发试验前PRE和激发试验后P10的血清皮质醇水平显著降低(P＜0.05),激发试验后P30的ACTH和WBC水平显著降低(P＜0.05,P＜0.01)、SOD活性水平显著升高(P＜0.05)。结论: 橘皮素能有效缓解高强度运动诱发的人体皮质醇应激反应,抑制皮质醇过度分泌,提升人体抗氧化能力,加速体内炎症消除,促进身体机能恢复。

关键词: 橘皮素, 运动, 应激, 抗阻运动, 血清皮质醇

Abstract: Objective: To investigate the effects of 4-week tangeretin supplementation on cortisol stress response induced by high-intensity resistance exercise. Methods: Twenty-four sprinters were paired and randomly divided into experimental group (EG) and control group (CG). EG orally took supplement with tangeretin (200 mg/day) and CG took placebo for 4 weeks. Before and after the 4-week intervention, all sprinters performed a set of high-intensity resistance exercise (shoulder press, squat, bench press and deadlift, 10 RM, 4 sets per movement) to stimulate their cortisol stress responses. Serum levels of cortisol, adreno-corticotropic hormone (ACTH), superoxide dismutase (SOD), white blood cell count (WBC) and blood glucose were obtained by collecting blood sample before the exercise (PRE), immediately after the exercise (P0), and at 10 (P10), 20 (P20), and 30 minutes (P30) after the exercise. Results: Compared with the same period before the intervention, after the 4-week tangeretin intervention, EXP showed significantly reduced serum cortisol level at PRE (P=0.017), P10 (P=0.010), P20 and P30 (P＜0.05 or P＜0.01), and significantly reduced WBC at PRE, ACTH at P10 (P=0.037) and WBC and ACTH at P30 (P＜0.05). Compared with CTROL, EXP showed significantly lower levels of the serum cortisol at PRE and P10 (P＜0.05), and significantly lower levels of the ACTH (P＜0.05) and WBC (P＜0.01) at P30, and significantly increased level of the SOD activity at P30 (P＜0.05). Conclusion: Tangeretin supplementation can significantly alleviate the cortisol stress response induced by high-intensity resistance exercise, inhibit the excessive secretion of cortisol, enhance antioxidant capacity, accelerate the elimination of inflammation in the body, and promote the recovery of body functions.

Key words: tangeretin, exercise, stress, resistance exercise, serum cortisol

中图分类号:

G804.5

刘猛, 莫仕围, 周志钦, 高炳宏. 橘皮素对高强度运动诱发的人体皮质醇应激反应的影响^*[J]. 中国应用生理学杂志, 2021, 37(5): 523-528.

LIU Meng, MO Shi-wei , ZHOU Zhi-qin , GAO Bing-hong. Effects of Tangeretin on cortisol stress response induced by high-intensity resistance exercise[J]. CJAP, 2021, 37(5): 523-528.

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橘皮素对高强度运动诱发的人体皮质醇应激反应的影响^*

Effects of Tangeretin on cortisol stress response induced by high-intensity resistance exercise

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